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dc.contributor.authorGray, Darren J
dc.contributor.authorMcManus, Donald P
dc.contributor.authorLi, Yuesheng
dc.contributor.authorWilliams, Gail M
dc.contributor.authorBergquist, Robert
dc.contributor.authorRoss, Allen G
dc.date.accessioned2017-05-11T12:30:44Z
dc.date.available2017-05-11T12:30:44Z
dc.date.issued2010
dc.date.modified2010-09-17T07:06:21Z
dc.identifier.issn1473-3099
dc.identifier.doi10.1016/S1473-3099(10)70099-2
dc.identifier.urihttp://hdl.handle.net/10072/34077
dc.description.abstractSchistosomiasis is a major neglected tropical disease, with more than 200 million people infected and close to 800 million at risk. The disease burden is estimated to exceed 70 million disability-adjusted life-years. The anthelmintic drug praziquantel is highly effective in killing adult schistosome worms, but it is unable to kill developing schistosomes and so does not prevent reinfection. As a result, current praziquantel-based control programmes in Asia and sub-Saharan Africa are not effective or sustainable in the long term. The control of neglected tropical diseases, including schistosomiasis, is a funding priority for several donor agencies, with over US$350 million committed until 2013. Here we put forward an argument that donor funds would be more effectively spent on the development of a multi-faceted, integrated control programme, which would have a greater and longer lasting effect on disease transmission than the current chemotherapy-based programmes. The development of a transmission-blocking vaccine is also of great importance. A multi-faceted integrated control programme that incorporates a vaccine, even if only partly effective, has the potential to eliminate schistosomiasis. This integrated-approach model has the potential to improve the health of a billion of the world's poorest people and its effect cannot be underestimated.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherThe Lancet Publishing Group
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom733
dc.relation.ispartofpageto736
dc.relation.ispartofissue10
dc.relation.ispartofjournalThe Lancet Infectious Diseases
dc.relation.ispartofvolume10
dc.rights.retentionY
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchMedical Microbiology
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchcode1103
dc.subject.fieldofresearchcode1108
dc.subject.fieldofresearchcode1117
dc.titleSchistosomiasis Elimination: Lessons from the Past Guide the Future
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Health, School of Medicine
gro.date.issued2010
gro.hasfulltextNo Full Text
gro.griffith.authorGray, Darren
gro.griffith.authorMcManus, Don P.
gro.griffith.authorLi, Yuesheng
gro.griffith.authorRoss, Allen G.


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