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dc.contributor.authorPolit, Deniseen_US
dc.contributor.authorGillespie, Brigiden_US
dc.date.accessioned2017-05-03T14:33:15Z
dc.date.available2017-05-03T14:33:15Z
dc.date.issued2010en_US
dc.date.modified2010-09-21T06:56:49Z
dc.identifier.issn01606891en_US
dc.identifier.doi10.1002/nur.20386en_AU
dc.identifier.urihttp://hdl.handle.net/10072/34148
dc.description.abstractIntention-to-treat (ITT) in randomized controlled trials involves keeping participants in the treatment groups to which they were randomized regardless of whether they withdraw following randomization. Intention-to-treat is a strategy for maintaining the integrity of randomization and strengthening the trial's internal validity. Although ITT is advocated by the Consolidated Standards of Reporting Trials (CONSORT) guidelines, there is confusion about what ITT means and little specific advice on how to achieve it. The purpose of this article is to present definitions of ITT and to suggest strategies for implementing ITT as a total design strategy in nursing clinical trials. Recommendations are offered regarding study planning, study design, subject retention, sampling, data collection, data analysis, and reporting within the context of ITT.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherWileyen_US
dc.publisher.placeUnited Statesen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom355en_US
dc.relation.ispartofpageto368en_US
dc.relation.ispartofissue4en_US
dc.relation.ispartofjournalResearch in Nursing & Healthen_US
dc.relation.ispartofvolume33en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchNursing not elsewhere classifieden_US
dc.subject.fieldofresearchcode111099en_US
dc.titleIntention-to-treat in randomized controlled trials: Recommendations for a total trial strategyen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Nursing and Midwiferyen_US
gro.date.issued2010
gro.hasfulltextNo Full Text


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