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dc.contributor.authorFagan, Vincent
dc.contributor.authorHussein, Waleed M
dc.contributor.authorSu, Mei
dc.contributor.authorGiddam, Ashwini K
dc.contributor.authorBatzloff, Michael R
dc.contributor.authorGood, Michael F
dc.contributor.authorToth, Istvan
dc.contributor.authorSimerska, Pavla
dc.date.accessioned2017-07-09T22:10:52Z
dc.date.available2017-07-09T22:10:52Z
dc.date.issued2017
dc.identifier.issn1439-4227
dc.identifier.doi10.1002/cbic.201600639
dc.identifier.urihttp://hdl.handle.net/10072/341624
dc.description.abstractFour group A streptococcal glycolipopeptide vaccine candidates with different lipidic adjuvanting moieties were prepared and characterized. The immunogenicity of the compounds was evaluated by macrophage and dendritic cell uptake studies and by in vivo quantification of systemic IgG antibody by ELISA. Three of the candidates showed significant induction of the IgG response.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherJohn Wiley & Sons
dc.relation.ispartofpagefrom545
dc.relation.ispartofpageto553
dc.relation.ispartofjournalChemBioChem
dc.relation.ispartofvolume18
dc.subject.fieldofresearchInorganic Chemistry not elsewhere classified
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry
dc.subject.fieldofresearchBiochemistry and Cell Biology
dc.subject.fieldofresearchcode030299
dc.subject.fieldofresearchcode0304
dc.subject.fieldofresearchcode0601
dc.titleSynthesis, Characterization and Immunological Evaluation of Self-Adjuvanting Group A Streptococcal Vaccine Candidates Bearing Various Lipidic Adjuvanting Moieties
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorBatzloff, Michael R.
gro.griffith.authorGood, Michael F.


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