Show simple item record

dc.contributor.authorMahizir, Dayana
dc.contributor.authorBriffa, Jessica F
dc.contributor.authorHryciw, Deanne H
dc.contributor.authorWadley, Glenn D
dc.contributor.authorMoritz, Karen M
dc.contributor.authorWlodek, Mary E
dc.date.accessioned2017-07-17T04:37:38Z
dc.date.available2017-07-17T04:37:38Z
dc.date.issued2016
dc.identifier.issn1613-4125
dc.identifier.doi10.1002/mnfr.201500289
dc.identifier.urihttp://hdl.handle.net/10072/341900
dc.description.abstractObesity is a major public health crisis, with 1.6 billion adults worldwide being classified as overweight or obese in 2014. Therefore, it is not surprising that the number of women who are overweight or obese at the time of conception is increasing. Obesity during pregnancy is associated with the development of gestational diabetes and preeclampsia. The developmental origins of health and disease hypothesis proposes that perturbations during critical stages of development can result in adverse fetal changes that leads to an increased risk of developing diseases in adulthood. Of particular concern, children born to obese mothers are at a greater risk of developing cardiometabolic disease. One subset of the population who are predisposed to developing obesity are children born small for gestational age, which occurs in 10% of pregnancies worldwide. Epidemiological studies report that these growth-restricted children have an increased susceptibility to type 2 diabetes, obesity, and hypertension. Importantly during pregnancy, growth-restricted females have a higher risk of developing cardiometabolic disease, indicating that they may have an exacerbated phenotype if they are also overweight or obese. Thus, the development of early pregnancy interventions targeted to obese mothers may prevent their children from developing cardiometabolic disease in adulthood.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherWiley - VCH Verlag GmbH & Co. KGaA
dc.relation.ispartofpagefrom8
dc.relation.ispartofpageto17
dc.relation.ispartofissue1
dc.relation.ispartofjournalMolecular Nutrition and Food Research
dc.relation.ispartofvolume60
dc.subject.fieldofresearchPublic Health and Health Services not elsewhere classified
dc.subject.fieldofresearchFood Sciences
dc.subject.fieldofresearchNutrition and Dietetics
dc.subject.fieldofresearchPublic Health and Health Services
dc.subject.fieldofresearchcode111799
dc.subject.fieldofresearchcode0908
dc.subject.fieldofresearchcode1111
dc.subject.fieldofresearchcode1117
dc.titleMaternal obesity in females born small: Pregnancy complications and offspring disease risk
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorSkelly, Deanne


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record