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dc.contributor.authorHay, Iain D
dc.contributor.authorWang, Yajie
dc.contributor.authorMoradali, Mohammed F
dc.contributor.authorRehman, Zahid U
dc.contributor.authorRehm, Bernd HA
dc.date.accessioned2017-07-28T03:12:43Z
dc.date.available2017-07-28T03:12:43Z
dc.date.issued2014
dc.identifier.issn1462-2912
dc.identifier.doi10.1111/1462-2920.12389
dc.identifier.urihttp://hdl.handle.net/10072/342773
dc.description.abstractA vast range of extracellular polysaccharides are produced by bacteria in order to adapt to and thrive in diverse environmental niches. Many of these polymers have attracted great attention due to their implication in biofilm formation, capsule formation, virulence, or for their potential medical and industrial uses. One important exopolysaccharide, alginate, is produced by various Pseudomonas spp. and Azotobacter vinelandii. Alginate is of particular interest due to its role in the pathogenesis of Pseudomonas aeruginosa lung infection in cystic fibrosis patients. Here, we will discuss the genetic organization and distribution of the genes involved in the biosynthesis of this significant polymer. The complex regulatory networks involved in the production of bacterial alginate will be reviewed, including transcriptional, posttranscriptional and posttranslational forms of regulation.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley-Blackwell Publishing
dc.relation.ispartofpagefrom2997
dc.relation.ispartofpageto3011
dc.relation.ispartofissue10
dc.relation.ispartofjournalEnvironmental Microbiology
dc.relation.ispartofvolume16
dc.subject.fieldofresearchEvolutionary Biology not elsewhere classified
dc.subject.fieldofresearchEvolutionary Biology
dc.subject.fieldofresearchMicrobiology
dc.subject.fieldofresearchcode060399
dc.subject.fieldofresearchcode0603
dc.subject.fieldofresearchcode0605
dc.titleGenetics and regulation of bacterial alginate production
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorRehm, Bernd


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