Show simple item record

dc.contributor.authorSimmonds, Michael J
dc.contributor.authorSabapathy, Surendran
dc.contributor.authorGass, Gregory C
dc.contributor.authorMarshall-Gradisnik, Sonya M
dc.contributor.authorHaseler, Luke J
dc.contributor.authorChristy, Rhys M
dc.contributor.authorMinahan, Clare L
dc.contributor.editorJ.-F. Stoltz, S. Forconi, F. Jung, H. Niimi
dc.date.accessioned2017-05-03T13:17:42Z
dc.date.available2017-05-03T13:17:42Z
dc.date.issued2010
dc.date.modified2010-09-30T09:14:53Z
dc.identifier.issn1386-0291
dc.identifier.doi10.3233/CH-2010-1333
dc.identifier.urihttp://hdl.handle.net/10072/34329
dc.description.abstractImpaired heart rate variability (HRV)and haemorheology are independently associated with cardiovascular disease and diabetic complications. The aim of the present study was to investigate the relationships between parameters of HRV,and red blood cell (RBC) aggregation and deformability, in older women with type 2 diabetes. Twenty women (age 69 ᠲ yr) with uncomplicated type 2 diabetes and twenty controls (age 69 ᠳ yr) participated in the study. Beat-to-beat cardiac (RR) intervals over 5 min were analysed for HRV parameters in the time and frequency domains. Blood was sampled for RBC deformability, as well as RBC aggregation in two suspending mediums: haematocrit adjusted plasma and 3% dextran 70. RBC aggregation was increased and HRV was impaired for those with type 2 diabetes when compared with control. RBC aggregation was negatively related to low frequency power of HRV, and was positively related to high frequency power of HRV, for subjects with type 2 diabetes. RBC deformability was positively related to HRV only for those with type 2 diabetes. Impaired haemorheology is associated with reduced HRV in older women with type 2 diabetes, suggesting changes in the microcirculation may result in impaired modulation of cardiac cycles.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherIOS Press
dc.publisher.placeNetherlands
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom57
dc.relation.ispartofpageto68
dc.relation.ispartofjournalClinical Hemorheology and Microcirculation
dc.relation.ispartofvolume46
dc.rights.retentionN
dc.subject.fieldofresearchCardiovascular medicine and haematology not elsewhere classified
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchcode320199
dc.subject.fieldofresearchcode3202
dc.titleHeart rate variability is related to impaired haemorheology in older women with type 2 diabetes
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.date.issued2010
gro.hasfulltextNo Full Text
gro.griffith.authorMinahan, Clare L.
gro.griffith.authorSabapathy, Surendran
gro.griffith.authorSimmonds, Michael J.
gro.griffith.authorMarshall-Gradisnik, Sonya M.


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record