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dc.contributor.authorGumpena, Rajesh
dc.contributor.authorKishor, Chandan
dc.contributor.authorGanji, Roopa Jones
dc.contributor.authorAddlagatta, Anthony
dc.date.accessioned2017-08-15T04:23:55Z
dc.date.available2017-08-15T04:23:55Z
dc.date.issued2011
dc.identifier.issn1860-7187
dc.identifier.doi10.1002/cmdc.201100298
dc.identifier.urihttp://hdl.handle.net/10072/344226
dc.description.abstractFlipping out! The X-ray crystal structure of L-α,γ-diaminobutyric acid (DABA, shown in magenta) in complex with an M1 family aminopeptidase reveals that the γ-amino group displaces the α-amino group from its original position (as in the complex with lysine, shown in cyan), which in turn results in a peptide flip at Met 260.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofpagefrom1971
dc.relation.ispartofpageto1976
dc.relation.ispartofissue11
dc.relation.ispartofjournalChemMedChem
dc.relation.ispartofvolume6
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry not elsewhere classified
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry
dc.subject.fieldofresearchOrganic Chemistry
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchcode030499
dc.subject.fieldofresearchcode0304
dc.subject.fieldofresearchcode0305
dc.subject.fieldofresearchcode1115
dc.titleDiscovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorKishor, Chandan


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