dc.contributor.author | Gumpena, Rajesh | |
dc.contributor.author | Kishor, Chandan | |
dc.contributor.author | Ganji, Roopa Jones | |
dc.contributor.author | Addlagatta, Anthony | |
dc.date.accessioned | 2017-08-15T04:23:55Z | |
dc.date.available | 2017-08-15T04:23:55Z | |
dc.date.issued | 2011 | |
dc.identifier.issn | 1860-7187 | |
dc.identifier.doi | 10.1002/cmdc.201100298 | |
dc.identifier.uri | http://hdl.handle.net/10072/344226 | |
dc.description.abstract | Flipping out! The X-ray crystal structure of L-α,γ-diaminobutyric acid (DABA, shown in magenta) in complex with an M1 family aminopeptidase reveals that the γ-amino group displaces the α-amino group from its original position (as in the complex with lysine, shown in cyan), which in turn results in a peptide flip at Met 260. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Wiley | |
dc.relation.ispartofpagefrom | 1971 | |
dc.relation.ispartofpageto | 1976 | |
dc.relation.ispartofissue | 11 | |
dc.relation.ispartofjournal | ChemMedChem | |
dc.relation.ispartofvolume | 6 | |
dc.subject.fieldofresearch | Medicinal and Biomolecular Chemistry not elsewhere classified | |
dc.subject.fieldofresearch | Medicinal and Biomolecular Chemistry | |
dc.subject.fieldofresearch | Organic Chemistry | |
dc.subject.fieldofresearch | Pharmacology and Pharmaceutical Sciences | |
dc.subject.fieldofresearchcode | 030499 | |
dc.subject.fieldofresearchcode | 0304 | |
dc.subject.fieldofresearchcode | 0305 | |
dc.subject.fieldofresearchcode | 1115 | |
dc.title | Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Kishor, Chandan | |