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  • Protein and Peptide Biopharmaceuticals: An Overview

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    AgyeiPUB2177.pdf (692.9Kb)
    Author(s)
    Agyei, Dominic
    Ahmed, Ishtiaq
    Akram, Zain
    Iqbal, Hafiz MN
    Danquah, Michael K
    Griffith University Author(s)
    Ahmed, Ishtiaq
    Akram, Zain
    Year published
    2017
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    Abstract
    Bioactive proteins and peptides are recognised as novel therapeutic molecules with varying biological properties for potential medical applications. Development of protein and peptidebased therapeutic products for human use is growing steadily as they continue to receive an increasing rate of approval by the United States Food and Drugs Administration (US FDA). In this short review, we describe the current status and methodologies involved in the synthesis of protein and peptide biopharmaceuticals with an emphasis on the drivers and restrains to their exploitation in the therapeutic products sector.Bioactive proteins and peptides are recognised as novel therapeutic molecules with varying biological properties for potential medical applications. Development of protein and peptidebased therapeutic products for human use is growing steadily as they continue to receive an increasing rate of approval by the United States Food and Drugs Administration (US FDA). In this short review, we describe the current status and methodologies involved in the synthesis of protein and peptide biopharmaceuticals with an emphasis on the drivers and restrains to their exploitation in the therapeutic products sector.
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    Journal Title
    Protein & Peptide Letters
    Volume
    24
    Issue
    2
    DOI
    https://doi.org/10.2174/0929866523666161222150444
    Copyright Statement
    © 2017 Bentham Science Publishers. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal website for access to the definitive, published version.
    Subject
    Medicinal and Biomolecular Chemistry not elsewhere classified
    Medicinal and Biomolecular Chemistry
    Biochemistry and Cell Biology
    Publication URI
    http://hdl.handle.net/10072/344370
    Collection
    • Journal articles

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