Show simple item record

dc.contributor.authorKhosravi Boroujeni, Hossein
dc.contributor.authorNikbakht Nasrabadi, Elham
dc.contributor.authorPaukste, Ernesta
dc.contributor.authorKhalesi, Saman
dc.date.accessioned2017-08-28T07:14:34Z
dc.date.available2017-08-28T07:14:34Z
dc.date.issued2017
dc.identifier.issn1097-0010en_US
dc.identifier.doi10.1002/jsfa.8361en_US
dc.identifier.urihttp://hdl.handle.net/10072/345043
dc.description.abstractHypertension is a major risk factor for cardiovascular disease, myocardial infarction, stroke and renal failure. Sesame consumption may benefit blood pressure (BP) owing to its high polyunsaturated fatty acid, fibre, phytosterol and lignan contents. To clarify this, a systematic review and meta-analysis of controlled trials was conducted. The PubMed (MEDLINE), Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Cochrane Library (Central) databases were systematically searched until August 2016. Eight controlled trials with a total of 843 participants met the eligibility criteria. A random effect meta-analysis showed that sesame consumption can reduce systolic BP (−7.83 mmHg, 95% CI: −14.12, −1.54; P < 0.05, I2 = 99%) and diastolic BP (−5.83 mmHg, 95% CI: −9.58, −2.08; P < 0.01, I2 = 98%). To reduce the heterogeneity, the meta-analysis was limited to high methodology quality trials (n = 4), which resulted in a significant reduction in systolic BP (−3.23 mmHg, 95% CI: −5.67, −0.79; I2 = 33%) and a non-significant reduction in diastolic BP (−2.08 mmHg, 95% CI: −4.85, 0.69; I2 = 62%). This study concluded that sesame consumption can reduce systolic and diastolic BP. However, further investigations with larger sample sizes and better methodology quality are required to confirm the BP-lowering effect of sesame consumption.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherJohn Wiley & Sonsen_US
dc.relation.ispartofpagefrom3087en_US
dc.relation.ispartofpageto3094en_US
dc.relation.ispartofissue10en_US
dc.relation.ispartofjournalJournal of the Science of Food and Agricultureen_US
dc.relation.ispartofvolume97en_US
dc.subject.fieldofresearchCardiovascular Medicine and Haematology not elsewhere classifieden_US
dc.subject.fieldofresearchcode110299en_US
dc.titleCan sesame consumption improve blood pressure? A systematic review and meta-analysis of controlled trialsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Medicineen_US
gro.hasfulltextNo Full Text


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record