• myGriffith
    • Staff portal
    • Contact Us⌄
      • Future student enquiries 1800 677 728
      • Current student enquiries 1800 154 055
      • International enquiries +61 7 3735 6425
      • General enquiries 07 3735 7111
      • Online enquiries
      • Staff phonebook
    View Item 
    •   Home
    • Griffith Research Online
    • Journal articles
    • View Item
    • Home
    • Griffith Research Online
    • Journal articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

  • All of Griffith Research Online
    • Communities & Collections
    • Authors
    • By Issue Date
    • Titles
  • This Collection
    • Authors
    • By Issue Date
    • Titles
  • Statistics

  • Most Popular Items
  • Statistics by Country
  • Most Popular Authors
  • Support

  • Contact us
  • FAQs
  • Admin login

  • Login
  • Preparation and characterization of cyclodextrin functionalized polydimethylsiloxane films via interfacial self-assembly

    Author(s)
    Huang, Tiefan
    Niu, Yubiao
    Zhang, Fang
    Zhang, Lin
    Chen, Shengfu
    Yu, Qiming Jimmy
    Griffith University Author(s)
    Yu, Jimmy J.
    Year published
    2017
    Metadata
    Show full item record
    Abstract
    Functionalized surfaces have many applications in areas such as sensor technology, selective adsorbents and controlled drug release. In this paper, polydimethylsiloxane (PDMS) films functionalized with a layer of cyclodextrin (CD) were prepared by using a facile and practical interfacial molecular self-assembly strategy. The surface and film structures were characterized and confirmed with FTIR-ATR and XPS spectroscopy. The prepared films were also tested for adsorption capacities for molecules of congo red and methylene blue and inclusion capabilities for antibacterial drug ciprofloxacin hydrochloride. For the CD layer ...
    View more >
    Functionalized surfaces have many applications in areas such as sensor technology, selective adsorbents and controlled drug release. In this paper, polydimethylsiloxane (PDMS) films functionalized with a layer of cyclodextrin (CD) were prepared by using a facile and practical interfacial molecular self-assembly strategy. The surface and film structures were characterized and confirmed with FTIR-ATR and XPS spectroscopy. The prepared films were also tested for adsorption capacities for molecules of congo red and methylene blue and inclusion capabilities for antibacterial drug ciprofloxacin hydrochloride. For the CD layer preparation, amphiphilic cyclodextrin (am-β-CD) was synthesized by region-selective modification of the primary hydroxyl groups of β-cyclodextrin with long aliphatic chains, and then self-assembled on the interface between water and a PDMS organic casting solution. A layer of am-β-CD molecules was assembled onto the surface of the PDMS substrate via the mechanisms of molecular chain entanglements and hydrophobic interactions, which was confirmed by various characterization techniques. Fluorescent molecular staining experiments indicated that the self-assembled cyclodextrins layer on the PDMS substrate surface mostly retained the ability to include guest molecules. Adsorption tests showed that the functionalized films had a much higher adsorption capacity for the dye molecules than that of bare PDMS films. Inclusion experiments also showed that ciprofloxacin hydrochloride loaded functionlized PDMS films exhibited excellent antibacterial performance, indicating that the films could be used as a reservoir to store small drug molecules. All these results demonstrated that the novel films prepared could have potential applications in various areas, such as drug-loaded system and water purification.
    View less >
    Journal Title
    Applied Materials Today
    Volume
    9
    DOI
    https://doi.org/10.1016/j.apmt.2017.07.003
    Subject
    Condensed matter physics
    Chemical engineering not elsewhere classified
    Materials engineering
    Nanotechnology
    Publication URI
    http://hdl.handle.net/10072/346279
    Collection
    • Journal articles

    Footer

    Disclaimer

    • Privacy policy
    • Copyright matters
    • CRICOS Provider - 00233E
    • TEQSA: PRV12076

    Tagline

    • Gold Coast
    • Logan
    • Brisbane - Queensland, Australia
    First Peoples of Australia
    • Aboriginal
    • Torres Strait Islander