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dc.contributor.authorMaqbool, Faheem
dc.contributor.authorAbid, Amman
dc.contributor.authorAhmed, Ishtiaq
dc.date.accessioned2017-09-21T01:02:56Z
dc.date.available2017-09-21T01:02:56Z
dc.date.issued2017
dc.identifier.issn1811-7775en_US
dc.identifier.doi10.3923/ijp.2017.773.784en_US
dc.identifier.urihttp://hdl.handle.net/10072/346725
dc.description.abstractDrug discovery in different time frames provides a reflection in the struggle of scientists to generate synthetic products from a natural source. The complex processes exist in the development of the new drug from novel ideas. The duration may vary 10-15 year with estimation cost of $1.5 billion. The stratification of different assays involved in development phase leads to the acceptability of drug molecule. In the discovery phase, implementation of powerful techniques such as combinatorial chemistry and molecular modeling has also participated in the identification of drug target molecules. The advancement in molecular biology especially genomic science has also imparted a profound role in the discovery phase. However, with bioinformatics branch, it allows us to derive more suitable points for attacking the drug molecule in different disease conditions. However, the review will describe the preclinical stages, identification and validation of target through HTS (high throughput screening assay) and finally approval of drug molecule for further clinical development.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherAsian Network for Scientific Information (ANSINET)en_US
dc.relation.ispartofpagefrom773en_US
dc.relation.ispartofpageto784en_US
dc.relation.ispartofissue7en_US
dc.relation.ispartofjournalInternational Journal of Pharmacologyen_US
dc.relation.ispartofvolume13en_US
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences not elsewhere classifieden_US
dc.subject.fieldofresearchcode111599en_US
dc.titleDrug discovery processes to drug targeting mechanismsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
dc.description.versionPost-printen_US
gro.rights.copyright© 2017 Asian Network for Scientific Information. This is the author-manuscript version of this paper. Reproduced in accordance with the copyright policy of the publisher. Please refer to the journal website for access to the definitive, published version.en_US
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