dc.contributor.author | Heras, Begona | |
dc.contributor.author | Shouldice, Stephen R | |
dc.contributor.author | Totsika, Makrina | |
dc.contributor.author | Scanlon, Martin J | |
dc.contributor.author | Schembri, Mark A | |
dc.contributor.author | Martin, Jennifer L | |
dc.date.accessioned | 2017-09-22T03:48:52Z | |
dc.date.available | 2017-09-22T03:48:52Z | |
dc.date.issued | 2009 | |
dc.identifier.issn | 1740-1526 | |
dc.identifier.doi | 10.1038/nrmicro2087 | |
dc.identifier.uri | http://hdl.handle.net/10072/347146 | |
dc.description.abstract | If DNA is the information of life, then proteins are the machines of life — but they must be assembled and correctly folded to function. A key step in the protein-folding pathway is the introduction of disulphide bonds between cysteine residues in a process called oxidative protein folding. Many bacteria use an oxidative protein-folding machinery to assemble proteins that are essential for cell integrity and to produce virulence factors. Although our current knowledge of this machinery stems largely from Escherichia coli K-12, this view must now be adjusted to encompass the wider range of disulphide catalytic systems present in bacteria. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Nature Publishing Group | |
dc.relation.ispartofpagefrom | 215 | |
dc.relation.ispartofpageto | 225 | |
dc.relation.ispartofissue | 3 | |
dc.relation.ispartofjournal | Nature Reviews Microbiology | |
dc.relation.ispartofvolume | 7 | |
dc.subject.fieldofresearch | Microbiology | |
dc.subject.fieldofresearch | Microbiology not elsewhere classified | |
dc.subject.fieldofresearch | Medical microbiology | |
dc.subject.fieldofresearchcode | 3107 | |
dc.subject.fieldofresearchcode | 310799 | |
dc.subject.fieldofresearchcode | 3207 | |
dc.title | DSB proteins and bacterial pathogenicity | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Martin, Jennifer | |