The acidic nature of the CcmG redox-active center is important for cytochrome c maturation in Escherichia coli

View/ Open
File version
Version of Record (VoR)
Author(s)
Edeling, MA
Ahuja, U
Heras, B
Thony-Meyer, L
Martin, JL
Griffith University Author(s)
Year published
2004
Metadata
Show full item recordAbstract
Cytochrome c biogenesis in Escherichia coli is a complex process requiring at least eight genes (ccmABCDEFGH). One of these genes, ccmG, encodes a thioredoxin-like protein with unusually specific redox activity. Here, we investigate the basis for CcmG function and demonstrate the importance of acidic residues surrounding the redox-active center.Cytochrome c biogenesis in Escherichia coli is a complex process requiring at least eight genes (ccmABCDEFGH). One of these genes, ccmG, encodes a thioredoxin-like protein with unusually specific redox activity. Here, we investigate the basis for CcmG function and demonstrate the importance of acidic residues surrounding the redox-active center.
View less >
View less >
Journal Title
Journal of Bacteriology
Volume
186
Issue
12
Copyright Statement
© 2004 American Society for Microbiology. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
Subject
Biological sciences
Microbiology not elsewhere classified
Agricultural, veterinary and food sciences
Biomedical and clinical sciences