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  • The acidic nature of the CcmG redox-active center is important for cytochrome c maturation in Escherichia coli

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    Author(s)
    Edeling, MA
    Ahuja, U
    Heras, B
    Thony-Meyer, L
    Martin, JL
    Griffith University Author(s)
    Martin, Jennifer
    Year published
    2004
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    Abstract
    Cytochrome c biogenesis in Escherichia coli is a complex process requiring at least eight genes (ccmABCDEFGH). One of these genes, ccmG, encodes a thioredoxin-like protein with unusually specific redox activity. Here, we investigate the basis for CcmG function and demonstrate the importance of acidic residues surrounding the redox-active center.Cytochrome c biogenesis in Escherichia coli is a complex process requiring at least eight genes (ccmABCDEFGH). One of these genes, ccmG, encodes a thioredoxin-like protein with unusually specific redox activity. Here, we investigate the basis for CcmG function and demonstrate the importance of acidic residues surrounding the redox-active center.
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    Journal Title
    Journal of Bacteriology
    Volume
    186
    Issue
    12
    DOI
    https://doi.org/10.1128/JB.186.12.4030-4033.2004
    Copyright Statement
    © 2004 American Society for Microbiology. The attached file is reproduced here in accordance with the copyright policy of the publisher. Please refer to the journal's website for access to the definitive, published version.
    Subject
    Biological sciences
    Microbiology not elsewhere classified
    Agricultural, veterinary and food sciences
    Biomedical and clinical sciences
    Publication URI
    http://hdl.handle.net/10072/347581
    Collection
    • Journal articles

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