Outbreak of health care-associated Burkholderia cenocepacia bacteremia and infection attributed to contaminated sterile gel used for central line insertion under ultrasound guidance and other procedures
Author(s)
Shaban, Ramon Z
Maloney, Samuel
Gerrard, John
Collignon, Peter
Macbeth, Deborough
Cruickshank, Marilyn
Hume, Anna
Jennison, Amy V
Graham, Rikki MA
Bergh, Haakon
Wilson, Heather L
Derrington, Petra
Year published
2017
Metadata
Show full item recordAbstract
Background: We report an outbreak of Burkholderia cenocepacia bacteremia and infection in 11 patients
predominately in intensive care units caused by contaminated ultrasound gel used in central line
insertion and sterile procedures within 4 hospitals across Australia.
Methods: Burkholderia cenocepacia was first identified in the blood culture of a patient from the intensive
care unit at the Gold Coast University Hospital on March 26, 2017, with 3 subsequent cases identified
by April 7, 2017. The outbreak response team commenced investigative measures.
Results: The outbreak investigation identified the point source as ...
View more >Background: We report an outbreak of Burkholderia cenocepacia bacteremia and infection in 11 patients predominately in intensive care units caused by contaminated ultrasound gel used in central line insertion and sterile procedures within 4 hospitals across Australia. Methods: Burkholderia cenocepacia was first identified in the blood culture of a patient from the intensive care unit at the Gold Coast University Hospital on March 26, 2017, with 3 subsequent cases identified by April 7, 2017. The outbreak response team commenced investigative measures. Results: The outbreak investigation identified the point source as contaminated gel packaged in sachets for use within the sterile ultrasound probe cover. In total, 11 patient isolates of B cenocepacia with the same multilocus sequence type were identified within 4 hospitals across Australia. This typing was the same as identified in the contaminated gel isolate with single nucleotide polymorphism-based typing, demonstrating that all linked isolates clustered together. Conclusion: Arresting the national point-source outbreak within multiple jurisdictions was critically reliant on a rapid, integrated, and coordinated response and the use of informal professional networks to first identify it. All institutions where the product is used should look back at Burkholderia sp blood culture isolates for speciation to ensure this outbreak is no larger than currently recognized given likely global distribution
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View more >Background: We report an outbreak of Burkholderia cenocepacia bacteremia and infection in 11 patients predominately in intensive care units caused by contaminated ultrasound gel used in central line insertion and sterile procedures within 4 hospitals across Australia. Methods: Burkholderia cenocepacia was first identified in the blood culture of a patient from the intensive care unit at the Gold Coast University Hospital on March 26, 2017, with 3 subsequent cases identified by April 7, 2017. The outbreak response team commenced investigative measures. Results: The outbreak investigation identified the point source as contaminated gel packaged in sachets for use within the sterile ultrasound probe cover. In total, 11 patient isolates of B cenocepacia with the same multilocus sequence type were identified within 4 hospitals across Australia. This typing was the same as identified in the contaminated gel isolate with single nucleotide polymorphism-based typing, demonstrating that all linked isolates clustered together. Conclusion: Arresting the national point-source outbreak within multiple jurisdictions was critically reliant on a rapid, integrated, and coordinated response and the use of informal professional networks to first identify it. All institutions where the product is used should look back at Burkholderia sp blood culture isolates for speciation to ensure this outbreak is no larger than currently recognized given likely global distribution
View less >
Journal Title
American Journal of Infection Control
Volume
45
Issue
9
Subject
Nursing
Nursing not elsewhere classified
Health services and systems
Public health