Effectiveness of a mouthrinse containing active ingredients in addition to chlorhexidine and triclosan compared with chlorhexidine and triclosan rinses on plaque, gingivitis, supragingival calculus and extrinsic staining
Author(s)
Kumar, S
Patel, S
Tadakamadla, J
Tibdewal, H
Duraiswamy, P
Kulkarni, S
Year published
2013
Metadata
Show full item recordAbstract
Objectives: To assess the effectiveness of three different
mouthrinses – chlorhexidine, triclosan + sodium fluoride and
chlorhexidine + triclosan + sodium fluoride + zinc chloride – on
plaque, calculus, gingivitis and stains and to evaluate the occurrence
of adverse effects with these three treatments. Methods: Forty-eight
healthy subjects participated in a double-blind, randomized,
parallel experiment and were randomly allocated to any one of the
three experimental mouthrinses: group A (0.2% chlorhexidine (CHX)
gluconate), group B (0.03% triclosan + 0.025% sodium fluoride
(NaF) + 12% ethyl alcohol) or group C (0.2% CHX + ...
View more >Objectives: To assess the effectiveness of three different mouthrinses – chlorhexidine, triclosan + sodium fluoride and chlorhexidine + triclosan + sodium fluoride + zinc chloride – on plaque, calculus, gingivitis and stains and to evaluate the occurrence of adverse effects with these three treatments. Methods: Forty-eight healthy subjects participated in a double-blind, randomized, parallel experiment and were randomly allocated to any one of the three experimental mouthrinses: group A (0.2% chlorhexidine (CHX) gluconate), group B (0.03% triclosan + 0.025% sodium fluoride (NaF) + 12% ethyl alcohol) or group C (0.2% CHX + 0.3% triclosan + 0.3% NaF + 0.09% Zn chloride (ZnCl2). All the subjects were assessed for gingivitis, plaque, supragingival calculus and extrinsic stains at baseline and at the end of the 21-day experimental period. Results: There was a significant difference (P = 0.046) in the effectiveness for the prevention of gingivitis and plaque, with subjects of group A and group C presenting least and highest gingival and plaque scores, respectively. Significant differences (P = 0.03) were observed for the accumulation of supragingival calculus where the deposition of calculus in group A was nearly double that of the group B, and group B was most effective in the prevention of supragingival calculus. Highest deposition of extrinsic stains was in the group A followed by group C and group B. There was no significant difference between the three treatments for adverse events’ occurrence. Conclusions: CHX mouthrinse was most effective in controlling plaque and gingivitis but caused greatest deposition of extrinsic stains. Supragingival calculus deposition was least in triclosan + NaF group followed by CHX + triclosan + NaF + ZnCl2 and CHX. More than half of the subjects reported adverse events during the experimental phase.
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View more >Objectives: To assess the effectiveness of three different mouthrinses – chlorhexidine, triclosan + sodium fluoride and chlorhexidine + triclosan + sodium fluoride + zinc chloride – on plaque, calculus, gingivitis and stains and to evaluate the occurrence of adverse effects with these three treatments. Methods: Forty-eight healthy subjects participated in a double-blind, randomized, parallel experiment and were randomly allocated to any one of the three experimental mouthrinses: group A (0.2% chlorhexidine (CHX) gluconate), group B (0.03% triclosan + 0.025% sodium fluoride (NaF) + 12% ethyl alcohol) or group C (0.2% CHX + 0.3% triclosan + 0.3% NaF + 0.09% Zn chloride (ZnCl2). All the subjects were assessed for gingivitis, plaque, supragingival calculus and extrinsic stains at baseline and at the end of the 21-day experimental period. Results: There was a significant difference (P = 0.046) in the effectiveness for the prevention of gingivitis and plaque, with subjects of group A and group C presenting least and highest gingival and plaque scores, respectively. Significant differences (P = 0.03) were observed for the accumulation of supragingival calculus where the deposition of calculus in group A was nearly double that of the group B, and group B was most effective in the prevention of supragingival calculus. Highest deposition of extrinsic stains was in the group A followed by group C and group B. There was no significant difference between the three treatments for adverse events’ occurrence. Conclusions: CHX mouthrinse was most effective in controlling plaque and gingivitis but caused greatest deposition of extrinsic stains. Supragingival calculus deposition was least in triclosan + NaF group followed by CHX + triclosan + NaF + ZnCl2 and CHX. More than half of the subjects reported adverse events during the experimental phase.
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Journal Title
International Journal of Dental Hygiene
Volume
11
Issue
1
Subject
Dentistry
Dentistry not elsewhere classified