dc.contributor.author | Mitchell, Marion L | |
dc.contributor.author | Shum, David HK | |
dc.contributor.author | Mihala, Gabor | |
dc.contributor.author | Murfield, Jenny E | |
dc.contributor.author | Aitken, Leanne M | |
dc.date.accessioned | 2019-05-29T13:00:59Z | |
dc.date.available | 2019-05-29T13:00:59Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1036-7314 | |
dc.identifier.doi | 10.1016/j.aucc.2017.07.002 | |
dc.identifier.uri | http://hdl.handle.net/10072/349532 | |
dc.description.abstract | Background: Whilst there is a growing body of research exploring the effect of delirium in intensive care
unit (ICU) patients, the relationship between patient delirium and long-term cognitive impairment has
not been investigated in settings where low rates of delirium have been reported.
Objectives: To assess the associationbetweenthe incidence of delirium, durationofmechanical ventilation
and long term cognitive impairment in general ICU patients.
Methods: Prospective cohort study conducted in a tertiary level ICU in Queensland, Australia. Adult medical
and surgical ICU patients receiving ≥12 h mechanical ventilation were assessed for delirium on at
least one day. Cognitive impairment was assessed at three and/or six-months using the: Repeatable Battery
for the Assessment of Neuropsychological Status (RBANS); Trail Making Test (TMT) Part A and B; and
Mini-Mental State Examination (MMSE).
Results: Of 148 enrollees, 91 (61%) completed assessment atthree and/or sixmonths.Incidence of delirium
was 19%, with 41% cognitively impaired at three months and 24% remaining impaired at six months.
Delirium was associated with impaired cognition at six-months: mean TMT Part A scores (information
processing speed) were 7.86 s longer than those with no delirium (p = 0.03), and mean TMT Part B scores
(executive functioning) 24.0 s longer (p = 0.04).
Conclusions: ICU delirium was positively associated with impaired information processing speed and
executive functioning at six-months post-discharge for this cohort. Testing for cognitive impairment
with RBANS and TMT should be considered due to its greater sensitivity in comparison to the MMSE | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.publisher.place | United States | |
dc.relation.ispartofpagefrom | 204 | |
dc.relation.ispartofpageto | 211 | |
dc.relation.ispartofissue | 4 | |
dc.relation.ispartofjournal | Australian Critical Care | |
dc.relation.ispartofvolume | 31 | |
dc.subject.fieldofresearch | Clinical sciences | |
dc.subject.fieldofresearch | Nursing | |
dc.subject.fieldofresearch | Nursing not elsewhere classified | |
dc.subject.fieldofresearchcode | 3202 | |
dc.subject.fieldofresearchcode | 4205 | |
dc.subject.fieldofresearchcode | 420599 | |
dc.title | Long-term cognitive impairment and delirium in intensive care: A prospective cohort study | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
dcterms.license | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.description.version | Accepted Manuscript (AM) | |
gro.faculty | Griffith Health, School of Nursing and Midwifery | |
gro.description.notepublic | This publication has been entered into Griffith Research Online as an Advanced Online Version. | |
gro.rights.copyright | © 2017 Australian College of Critical Care Nurses Ltd. Published by Elsevier Australia. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited. | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Mitchell, Marion L. | |