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dc.contributor.authorHay, Iain D
dc.contributor.authorRehman, Zahid Ur
dc.contributor.authorGhafoor, Aamir
dc.contributor.authorRehm, Bernd HA
dc.date.accessioned2017-10-31T23:01:13Z
dc.date.available2017-10-31T23:01:13Z
dc.date.issued2010
dc.identifier.issn0268-2575
dc.identifier.doi10.1002/jctb.2372
dc.identifier.urihttp://hdl.handle.net/10072/350774
dc.description.abstractAlginates are polysaccharides with many industrial and medical uses, from food additives to encapsulation agents in the emerging transplantation technologies. Alginate is composed of variable proportions of β-D-mannuronic acid and α-L-guluronic acid linked by 1–4 glycosidic bonds. Traditionally, commercial alginate has been produced by farmed brown seaweeds, but this alginate suffers from heterogeneity in composition and quality partly due to environmental variation. Two bacterial genera, Pseudomonas and Azotobacter, are also capable of producing alginate as an exopolysaccharide. These bacterial alginate producers can provide the means to produce alginates with defined monomer composition and possibly through genetic and protein engineering may allow for the production of ‘tailor made’ bacterial alginates. The paper discusses the mechanisms behind alginate production in bacteria and how they may be used in the commercial production of alginates.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherJohn Wiley
dc.relation.ispartofpagefrom752
dc.relation.ispartofpageto759
dc.relation.ispartofissue6
dc.relation.ispartofjournalJournal of Chemical Technology and Biotechnology
dc.relation.ispartofvolume85
dc.subject.fieldofresearchBiochemistry and cell biology not elsewhere classified
dc.subject.fieldofresearchcode310199
dc.titleBacterial biosynthesis of alginates
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorRehm, Bernd


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