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dc.contributor.authorHsu, Hui-Chun
dc.contributor.authorTsai, Su-Yu
dc.contributor.authorWu, Shang-Liang
dc.contributor.authorJeang, Shiow-Roug
dc.contributor.authorHo, Mei-Yao
dc.contributor.authorLiou, Wen-Shiung
dc.contributor.authorChiang, An-Jen
dc.contributor.authorChang, Tsung-Hsien
dc.date.accessioned2017-11-28T12:01:17Z
dc.date.available2017-11-28T12:01:17Z
dc.date.issued2017
dc.identifier.issn0941-4355
dc.identifier.doi10.1007/s00520-017-3768-7
dc.identifier.urihttp://hdl.handle.net/10072/350776
dc.description.abstractPurpose: This study aimed to assess the incidence and difference of side effects among six courses of chemotherapy (C/T) in gynecological cancer patients. Methods: The study period was from Sep. 2010 to Dec. 2011 at the Kaohsiung Veterans General Hospital in Taiwan. The treating protocols, courses, and drugs of C/T in patient were considered according to the different malignant cancers and clinical conditions. The patient data of age, marriage status, education, religion, and experiences of C/T were collected. The patients’ or their families’ reported side effects of C/T were recorded daily from the beginning of C/T to the 10th day after C/T in each cycle and every course of C/T. Results: Total 89 patients enrolled into the study received total 450 courses of C/T. The mean age was 54.52 ± 11.02. Ovarian cancer was the most common malignant disease (64.0%). The most often combination of drugs used was Taxol and carboplatin (40.9%). Patients complained peripheral numbness of limbs, with the highest incidence of 58.6%. The side effects with incidence about 50% were decreased fatigue (55.0%) and hair loss (49.9%). Other side effects with different levels of incidence were also noticed, such as lack of appetite, changes in taste, and muscle ache. The incidences of peripheral limb numbness and hair loss were increased with following courses of C/T. The high incidence of fatigue did not show variation between different courses of C/T. Conclusion: This study revealed the incidence of side effects and occurrence timing during C/T in patients with gynecological cancer. These data provide substantial information to patients and their families to understand the potential side effects of C/T courses, which might increase their compliance in receiving adjuvant C/T. Relieving the side effects in C/T would be important to improve their quality of daily life and treatment willingness.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofpagefrom3457
dc.relation.ispartofpageto3464
dc.relation.ispartofissue11
dc.relation.ispartofjournalSupportive Care in Cancer
dc.relation.ispartofvolume25
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classified
dc.subject.fieldofresearchMedical and Health Sciences
dc.subject.fieldofresearchPsychology and Cognitive Sciences
dc.subject.fieldofresearchcode119999
dc.subject.fieldofresearchcode11
dc.subject.fieldofresearchcode17
dc.titleLongitudinal perceptions of the side effects of chemotherapy in patients with gynecological cancer
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorWu, Shang-Liang


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