Griffith Theses: Recent submissions
Now showing items 1-20 of 3358
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When do Anti-Corruption Agencies Need Society? A Study of the Nature and Effectiveness of Interactions between Horizontal Accountability Agencies and Social Accountability Actors in Three Australian States
(2018-08)Over the last three decades, globally, formal institutional enabling factors such as independence, powers and resources have been identified as important to the effective functioning of anti-corruption agencies (ACAs). ...GRIFFITH THESIS -
Characterisation of Staphylococcus aureus biofilms on Intravascular Catheters and associated Antimicrobial Resistance
(2018-06)Intravascular catheters (IVCs) are one of the most frequently used medical devices in hospitals. However, catheters are associated with serious IVC-related bloodstream infection (IVC-BSI), which causes high mortality and ...GRIFFITH THESIS -
Synthesis and Evaluation of Anti-Malarial Compounds Based On an Open Source Lead
(2018-06)Malaria infection is still considered a major global health problem. According to the WHO World Malaria Report 2017, 91 countries reported a total of 216 million cases of malaria in 2016, an increase of 5 million cases ...GRIFFITH THESIS -
Anti-malarial Drug Discovery from Australian Flora
(2018-09)Malaria is a mosquito-borne disease caused by the parasitic protozoan Plasmodium that is responsible for approximately half a million deaths every year. The vast majority of these deaths are caused by P. falciparum in ...GRIFFITH THESIS -
Speeding up Subgraph Isomorphism Search in Large Graphs
(2018-04)Graph is a widely used model to represent complicated data in many domains. Finding subgraph isomorphism is a fundamental function for many graph databases and data mining applications handling graph data. This thesis ...GRIFFITH THESIS -
Thermoregulatory function during exercise in the heat in heart failure
(2018-08)This thesis examined thermoregulatory responses in heart failure (HF) patients during exercise at a fixed relative intensity, and at an intensity that elicited a fixed rate of metabolic heat production (Hprod) in a warm ...GRIFFITH THESIS -
A New Synthetic Pathway Towards Legionaminic Acid
(2018-08)This thesis describes the results of a PhD project aimed at researching a new synthetic pathway towards legionaminic acid analogues. Legionaminic acid is a bacterial family of nonulosonic acids expressed in a terminal ...GRIFFITH THESIS -
Australian Engagement with China (1972-2018): A Cluster Concept Assessment
(2018-08)This study is in response to the persistent ambivalence characterising the Australian narrative on engagement with China. This ambivalence, between fear and friendship, can be framed as a tension between expected China ...GRIFFITH THESIS -
Piezoresistive Effect in 4H Silicon Carbide towards Mechanical Sensing in Harsh Environments
(2018-11)The fast-growing demand for mechanical sensors in harsh environments (e.g. mining/deep oil explorations, power/chemical plants and space explorations) urges the development of advanced materials which can replace silicon ...GRIFFITH THESIS -
Comparative genome analysis of Wolbachia strain wPanCI and wPanMK
(2018-07)Wolbachia are maternally transmitted endosymbionts that naturally infect approximately 40% of all insect species and impose a range of phenotypic effects upon their hosts, including feminization, parthenogenesis, cytoplasmic ...GRIFFITH THESIS -
Urban Public Space Governance and Its Implications for Qualities of Place
(2018-07)Urban public spaces are the loci of complex interactions among varied sectors of the society, containing stakeholders within the general public, the private sector, and state institutions. They are utilised for a wide ...GRIFFITH THESIS -
An Investigation Toward the Synthesis of Quinolinone Analogues as 1,4-Dihydroxy-2-Napthoate Prenyltransferase (MenA) Inhibitors
(2018-05)Bacterial drug resistance is a major concern to the World Health Organisation and the future of human health. Increasing resistance is consistently being observed to all commonly used antibiotic agents, and more recently ...GRIFFITH THESIS -
The Role of Chikungunya nsP3 in Regulating G3BP Activity, Stress Granule Formation and Drug Efficacy
(2018-06)Ras-GTPase activating protein SH3 domain binding proteins (G3BP) are a small family of RNA-binding proteins that have been implicated in regulating gene expression when a cell undergoes transformation or in response to ...GRIFFITH THESIS -
Addressing One-Dimensional Protein Structure Prediction Problems with Machine Learning Techniques
(2018-11-17)In this thesis we tackle the protein structure prediction subproblems listed previously, by applying state of the art deep learning techniques. The work in chapter 2 presents the method SPIDER. In this method, state of ...GRIFFITH THESIS -
Investigating natural products as new drug leads for malaria
(2018-07)Despite being preventable and treatable, malaria continues to be a significant threat to global health, particularly in the developing world. It is estimated that 90% of all malaria deaths occur in Africa and that 78% of ...GRIFFITH THESIS -
On the Potential of New Media to Enhance Environmental Activism in the Australian Context
(2017-12)Over the last two decades, positive claims have been consistently made worldwide about the potential of new media and more recently social media to enable easier, faster, and more universal political action and enhanced ...GRIFFITH THESIS -
GPS Data Analytics in Football: A Spotlight on Deceleration
(2018-06)Background: As technology has improved, the ability to gain data from player monitoring devices has become more prevalent in sport science, especially with the introduction of Global Positioning System (GPS) technology. ...GRIFFITH THESIS -
Qualitative Segmentation vs. Quantitative Segmentation in a Water Use Market: A Cost Benefit Approach
(2018-08)Attention has been directed towards audience segmentation due to the added value that it may deliver to a social marketing program. Segmentation offers one means to better utilise limited resources to enhance reach in ...GRIFFITH THESIS -
Toxicological Assessment of Photopolymers in Additive Manufacturing Using the Innovative Zebrafish Embryo Model
(2018-07)The capacity of additive manufacturing technologies to initiate speedy polymerization of solvent-free resins accounts for their utility in the construction of medical devices. Nonetheless, biocompatibility is an issue ...GRIFFITH THESIS -
From Negative to Positive Legislator? Response to Unconstitutional Legislative Omission As a Case Study in the Changing Roles of Constitutional Courts
(2018-08)An important but challenging development appears to be occurring in the character of some constitutional courts—a shift from their traditional role as a negative legislator to a significant role as a positive legislator. ...GRIFFITH THESIS