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dc.contributor.authorLeung, Becky
dc.contributor.authorYounger, John F
dc.contributor.authorStockton, Kellie
dc.contributor.authorMuller, Michael
dc.contributor.authorParatz, Jennifer
dc.date.accessioned2018-01-24T12:30:29Z
dc.date.available2018-01-24T12:30:29Z
dc.date.issued2017
dc.identifier.issn0305-4179
dc.identifier.doi10.1016/j.burns.2017.07.010
dc.identifier.urihttp://hdl.handle.net/10072/352203
dc.description.abstractObjective: Burn patients have prolonged derangements in metabolic, endocrine, cardiac and psychosocial systems, potentially impacting on their cardiovascular health. There are no studies on the risk of cardiovascular disease (CVD) after-burn. The aim of our study was to record lipid values and evaluate CVD risk in adult burn survivors. Methods: In a cross-sectional study patients 18 years with burn injury between 18–80% total burn surface area (TBSA) from 1998 to 2012 had total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides measured via finger prick. Means were compared to optimal ranges. Multivariate regression models were performed to assess the association oflipids withage, years after-burn and total body surface area % (TBSA). A p value <0.05 was considered significant. The Framingham General Cardiovascular Risk Score (FGCRS) was calculated. Results: Fifty patients were included in the study. Compared to optimal values, patients had low HDL and high triglycerides. Greater %TBSA was associated with statistically significant elevation of triglycerides (p=0.007) and total cholesterol/HDL ratio (p=0.027). The median FGCRS was 3.9% (low) 10-year risk of CVD with 82% of patients in the low-risk category. Patients involved in medium/high level of physical activity had optimal values of HDL, TC/ HDL and triglycerides despite the magnitude of TBSA%. Conclusion: Adult burn survivors had alterations in lipid profile proportional to TBSA, which could be modified by exercise, and no increase in overall formally predicted CVD risk in this cross sectional study.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofpagefrom1411
dc.relation.ispartofpageto1417
dc.relation.ispartofissue7
dc.relation.ispartofjournalBurns
dc.relation.ispartofvolume43
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchClinical sciences not elsewhere classified
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode320299
dc.titleCardiovascular risk profile in burn survivors
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorParatz, Jenny D.


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