dc.contributor.author | Leung, Becky | |
dc.contributor.author | Younger, John F | |
dc.contributor.author | Stockton, Kellie | |
dc.contributor.author | Muller, Michael | |
dc.contributor.author | Paratz, Jennifer | |
dc.date.accessioned | 2018-01-24T12:30:29Z | |
dc.date.available | 2018-01-24T12:30:29Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 0305-4179 | |
dc.identifier.doi | 10.1016/j.burns.2017.07.010 | |
dc.identifier.uri | http://hdl.handle.net/10072/352203 | |
dc.description.abstract | Objective: Burn patients have prolonged derangements in metabolic, endocrine, cardiac and
psychosocial systems, potentially impacting on their cardiovascular health. There are no
studies on the risk of cardiovascular disease (CVD) after-burn. The aim of our study was to
record lipid values and evaluate CVD risk in adult burn survivors.
Methods: In a cross-sectional study patients 18 years with burn injury between 18–80% total
burn surface area (TBSA) from 1998 to 2012 had total cholesterol, low density lipoprotein
(LDL), high density lipoprotein (HDL) and triglycerides measured via finger prick. Means were
compared to optimal ranges. Multivariate regression models were performed to assess the
association oflipids withage, years after-burn and total body surface area % (TBSA). A p value
<0.05 was considered significant. The Framingham General Cardiovascular Risk Score
(FGCRS) was calculated.
Results: Fifty patients were included in the study. Compared to optimal values, patients had
low HDL and high triglycerides. Greater %TBSA was associated with statistically significant
elevation of triglycerides (p=0.007) and total cholesterol/HDL ratio (p=0.027). The median
FGCRS was 3.9% (low) 10-year risk of CVD with 82% of patients in the low-risk category.
Patients involved in medium/high level of physical activity had optimal values of HDL, TC/
HDL and triglycerides despite the magnitude of TBSA%.
Conclusion: Adult burn survivors had alterations in lipid profile proportional to TBSA, which
could be modified by exercise, and no increase in overall formally predicted CVD risk in this
cross sectional study. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.relation.ispartofpagefrom | 1411 | |
dc.relation.ispartofpageto | 1417 | |
dc.relation.ispartofissue | 7 | |
dc.relation.ispartofjournal | Burns | |
dc.relation.ispartofvolume | 43 | |
dc.subject.fieldofresearch | Clinical sciences | |
dc.subject.fieldofresearch | Clinical sciences not elsewhere classified | |
dc.subject.fieldofresearchcode | 3202 | |
dc.subject.fieldofresearchcode | 320299 | |
dc.title | Cardiovascular risk profile in burn survivors | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.hasfulltext | No Full Text | |
gro.griffith.author | Paratz, Jenny D. | |