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dc.contributor.authorZhang, S
dc.contributor.authorZhao, H
dc.contributor.authorJohn, R
dc.date.accessioned2017-05-03T13:33:30Z
dc.date.available2017-05-03T13:33:30Z
dc.date.issued2001
dc.identifier.issn0956-5663
dc.identifier.doi10.1016/S0956-5663(01)00240-8
dc.identifier.urihttp://hdl.handle.net/10072/3555
dc.description.abstractTheoretical and practical insights into the design and development of immobilised enzyme inhibition biosensors are reported. A general mathematical expression relating the percent of enzyme inhibition (i.e. the analytical signal) to both the inhibitor concentration and the incubation time is presented. The relevant physical, chemical and biochemical parameters required by the model are developed and discussed in terms of the inhibition of acetylcholinesterase by the organophosphorous pesticide, paraoxon. A second enzyme, choline oxidase and an amperometric transducer are used to facilitate the determination acetylcholinesterase inhibitor.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoeng
dc.publisherPergamon
dc.publisher.placeUK
dc.relation.ispartofpagefrom1119
dc.relation.ispartofpageto1126
dc.relation.ispartofjournalBiosensors and Bioelectronics
dc.relation.ispartofvolume16
dc.subject.fieldofresearchAnalytical chemistry
dc.subject.fieldofresearchBiomedical engineering
dc.subject.fieldofresearchNanotechnology
dc.subject.fieldofresearchcode3401
dc.subject.fieldofresearchcode4003
dc.subject.fieldofresearchcode4018
dc.titleDevelopment of a qualitative relationship between inhibition percentage and both incubation time and inhibitor concentration for inhibition biosensors - theoretical and practical considerations
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Sciences, Griffith School of Environment
gro.date.issued2015-05-04T01:45:18Z
gro.hasfulltextNo Full Text
gro.griffith.authorZhao, Huijun
gro.griffith.authorZhang, Shanqing
gro.griffith.authorJohn, Richard


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