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  • Glyphosate–surfactant herbicide-induced reversible encephalopathy

    Author(s)
    Malhotra, RC
    Ghia, DK
    Cordato, DJ
    Beran, RG
    Griffith University Author(s)
    Beran, Roy G.
    Year published
    2010
    Metadata
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    Abstract
    Glyphosate-surfactant (GlySH) is a commonly used herbicide that has been used in attempted suicide. Most reports of GlySH toxicity in patients have followed ingestion of the commercial product ''Roundup" (Monsanto Ltd; Melbourne, Victoria, Australia), which consists of a mixture of glyphosate (as a isopropylanine salt) and a surfactant (polyoxyethyleneamine). Ingestion of Round-up is reported to cause significant toxicity including nausea, vomiting, oral and abdominal pain. Renal and hepatic impairment and pulmonary oedema may also occur. Impaired consciousness and encephalopathy have been reported as sequelae but there ...
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    Glyphosate-surfactant (GlySH) is a commonly used herbicide that has been used in attempted suicide. Most reports of GlySH toxicity in patients have followed ingestion of the commercial product ''Roundup" (Monsanto Ltd; Melbourne, Victoria, Australia), which consists of a mixture of glyphosate (as a isopropylanine salt) and a surfactant (polyoxyethyleneamine). Ingestion of Round-up is reported to cause significant toxicity including nausea, vomiting, oral and abdominal pain. Renal and hepatic impairment and pulmonary oedema may also occur. Impaired consciousness and encephalopathy have been reported as sequelae but there are limited data on the central nervous system (CNS) effects of Round-up toxicity. We report a 71-year-old male who attempted suicide with GlySH and developed a prolonged but reversible encephalopathy suggestive of acute CNS toxicity.
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    Journal Title
    Journal of Clinical Neuroscience
    Volume
    17
    Issue
    11
    DOI
    https://doi.org/10.1016/j.jocn.2010.02.026
    Subject
    Clinical sciences
    Neurosciences
    Publication URI
    http://hdl.handle.net/10072/35573
    Collection
    • Journal articles

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