An Unprecedented Blue Chromophore Found in Nature using a “Chemistry First” and Molecular Networking Approach: Discovery of Dactylocyanines A–H
Author(s)
Bonneau, Natacha
Chen, Guanming
Lachkar, David
Boufridi, Asmaa
Gallard, Jean-Francois
Retailleau, Pascal
Petek, Sylvain
Debitus, Cecile
Evanno, Laurent
Beniddir, Mehdi A
Poupon, Erwan
Griffith University Author(s)
Year published
2017
Metadata
Show full item recordAbstract
Guided by a “chemistry first” approach using molecular networking, eight new bright-blue colored natural compounds, namely dactylocyanines A–H (3–10), were isolated from the Polynesian marine sponge Dactylospongia metachromia. Starting from ilimaquinone (1), an hemisynthetic phishing probe (2) was prepared for annotating and matching structurally related natural substances in D. metachromia crude extract network. This strategy allowed characterizing for the first time in Nature the blue zwitterionic quinonoid chromophore. The solvatochromic properties of the latter are reported.Guided by a “chemistry first” approach using molecular networking, eight new bright-blue colored natural compounds, namely dactylocyanines A–H (3–10), were isolated from the Polynesian marine sponge Dactylospongia metachromia. Starting from ilimaquinone (1), an hemisynthetic phishing probe (2) was prepared for annotating and matching structurally related natural substances in D. metachromia crude extract network. This strategy allowed characterizing for the first time in Nature the blue zwitterionic quinonoid chromophore. The solvatochromic properties of the latter are reported.
View less >
View less >
Journal Title
Chemistry: A European Journal
Volume
23
Issue
58
Subject
Chemical sciences
Other chemical sciences not elsewhere classified