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dc.contributor.authorYelland, Michael J
dc.contributor.authorSweeting, Kent R
dc.contributor.authorLyftogt, John A
dc.contributor.authorShu, Kay Ng
dc.contributor.authorScuffham, Paul A
dc.contributor.authorEvans, Kerrie A
dc.date.accessioned2017-05-03T14:19:16Z
dc.date.available2017-05-03T14:19:16Z
dc.date.issued2011
dc.date.modified2014-08-28T05:08:22Z
dc.identifier.issn0306-3674
dc.identifier.doi10.1136/bjsm.2009.057968
dc.identifier.urihttp://hdl.handle.net/10072/35744
dc.description.abstractObjective: To compare the effectiveness and cost-effectiveness of eccentric loading exercises (ELE) with prolotherapy injections used singly and in combination for painful Achilles tendinosis. Design: A single-blinded randomised clinical trial. The primary outcome measure was the VISA-A questionnaire with a minimum clinically important change (MCIC) of 20 points on a 100 point scale. Setting: Five Australian private primary care centres. Participants: 43 patients with painful mid-portion Achilles tendinosis commenced and 40 completed the treatment protocols. Interventions: Participants were randomised to a 12 week program of ELE (n=15), or prolotherapy injections of hypertonic glucose with lignocaine alongside the affected tendon (n=14) or combined treatment (n=14). Main outcome measurements: VISA-A, pain, stiffness and limitation of activity scores and treatment costs were assessed prospectively over 12 months. Results: At 12 months, the proportions of participants achieving the MCIC for VISA-A scores were 73% for ELE, 79% for prolotherapy and 86% for combined treatment. Mean (95% CI) increases in VISA-A scores at 12 months were 23.7 (15.6 to 31.9) for ELE, 27.5 (12.8 to 42.2) for prolotherapy and 41.1 (29.3 to 52.9) for combined treatment. At 6 weeks and 12 months, these increases were significantly less for ELE than for combined treatment. Compared with ELE, reductions in stiffness and limitation of activity occurred earlier with prolotherapy and reductions in pain, stiffness and limitation of activity occurred earlier with combined treatment. Combined treatment had the lowest incremental cost per additional responder (AU$1539) compared with ELE. Conclusions: For Achilles tendinosis, prolotherapy and particularly ELE combined with prolotherapy give more rapid improvements in symptoms than ELE alone but long term VISA-A scores are similar.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.format.extent338492 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoeng
dc.publisherBMJ Publishing Group Ltd
dc.publisher.placeUnited Kingdom
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom421
dc.relation.ispartofpageto428
dc.relation.ispartofissue45
dc.relation.ispartofjournalBritish Journal of Sports Medicine
dc.relation.ispartofvolume2011
dc.rights.retentionY
dc.subject.fieldofresearchEngineering
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchEducation
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchSports science and exercise
dc.subject.fieldofresearchApplied and developmental psychology
dc.subject.fieldofresearchcode40
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode39
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode4207
dc.subject.fieldofresearchcode5201
dc.titleProlotherapy injections and eccentric loading exercises for painful Achilles tendinosis: a randomised trial
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Health, School of Medicine
gro.rights.copyright© The Author(s) 2010. The attached file is reproduced here in accordance with the copyright policy of the publisher. For information about this journal please refer to the journal's website or contact the authors.
gro.date.issued2011
gro.hasfulltextFull Text
gro.griffith.authorScuffham, Paul A.
gro.griffith.authorNg, Shu Kay Angus


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