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dc.contributor.authorYelland, Michaelen_US
dc.contributor.authorSweeting, Kenten_US
dc.contributor.authorLyftogt, Johnen_US
dc.contributor.authorNg, Shu-Kayen_US
dc.contributor.authorScuffham, Paulen_US
dc.contributor.authorEvans, Kerrieen_US
dc.date.accessioned2017-04-24T11:35:14Z
dc.date.available2017-04-24T11:35:14Z
dc.date.issued2011en_US
dc.date.modified2014-08-28T05:08:22Z
dc.identifier.issn03063674en_US
dc.identifier.doi10.1136/bjsm.2009.057968en_US
dc.identifier.urihttp://hdl.handle.net/10072/35744
dc.description.abstractObjective: To compare the effectiveness and cost-effectiveness of eccentric loading exercises (ELE) with prolotherapy injections used singly and in combination for painful Achilles tendinosis. Design: A single-blinded randomised clinical trial. The primary outcome measure was the VISA-A questionnaire with a minimum clinically important change (MCIC) of 20 points on a 100 point scale. Setting: Five Australian private primary care centres. Participants: 43 patients with painful mid-portion Achilles tendinosis commenced and 40 completed the treatment protocols. Interventions: Participants were randomised to a 12 week program of ELE (n=15), or prolotherapy injections of hypertonic glucose with lignocaine alongside the affected tendon (n=14) or combined treatment (n=14). Main outcome measurements: VISA-A, pain, stiffness and limitation of activity scores and treatment costs were assessed prospectively over 12 months. Results: At 12 months, the proportions of participants achieving the MCIC for VISA-A scores were 73% for ELE, 79% for prolotherapy and 86% for combined treatment. Mean (95% CI) increases in VISA-A scores at 12 months were 23.7 (15.6 to 31.9) for ELE, 27.5 (12.8 to 42.2) for prolotherapy and 41.1 (29.3 to 52.9) for combined treatment. At 6 weeks and 12 months, these increases were significantly less for ELE than for combined treatment. Compared with ELE, reductions in stiffness and limitation of activity occurred earlier with prolotherapy and reductions in pain, stiffness and limitation of activity occurred earlier with combined treatment. Combined treatment had the lowest incremental cost per additional responder (AU$1539) compared with ELE. Conclusions: For Achilles tendinosis, prolotherapy and particularly ELE combined with prolotherapy give more rapid improvements in symptoms than ELE alone but long term VISA-A scores are similar.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.format.extent338492 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherBMJ Publishing Group Ltden_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom421en_US
dc.relation.ispartofpageto428en_US
dc.relation.ispartofissue45en_US
dc.relation.ispartofjournalBritish Journal of Sports Medicineen_US
dc.relation.ispartofvolume2011en_US
dc.rights.retentionYen_US
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classifieden_US
dc.subject.fieldofresearchcode119999en_US
dc.titleProlotherapy injections and eccentric loading exercises for painful Achilles tendinosis: a randomised trialen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Health, School of Medicineen_US
gro.rights.copyrightCopyright remains with the authors 2010. The attached file is reproduced here in accordance with the copyright policy of the publisher. For information about this journal please refer to the journal's website or contact the authors.en_US
gro.date.issued2011
gro.hasfulltextFull Text


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