Pseudoceratinazole A: a novel bromotyrosine alkaloid from the Australian sponge Pseudoceratina sp

Mass-directed fractionation based on a Trypanosoma brucei brucei active fraction from the Australian sponge Pseudoceratina sp. led to the isolation of a novel bromotyrosine alkaloid, pseudoceratinazole A (1). Compound 1 is the first dimeric bromotyrosine alkaloid containing an imidazole-bridging moiety.Mass-directed fractionation based on a Trypanosoma brucei brucei active fraction from the Australian sponge Pseudoceratina sp. led to the isolation of a novel bromotyrosine alkaloid, pseudoceratinazole A (1). Compound 1 is the first dimeric bromotyrosine alkaloid containing an imidazole-bridging moiety.
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Journal Title

Tetrahedron Letters

Volume

Issue

DOI

https://doi.org/10.1016/j.tetlet.2010.07.052

Subject

Medicinal and biomolecular chemistry

Biologically active molecules

Organic chemistry

Publication URI

http://hdl.handle.net/10072/35940

Collection

Journal articles