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dc.contributor.authorYamada, R.en_US
dc.contributor.authorIturbe-Ormaetxe, I.en_US
dc.contributor.authorBrownlie, J.en_US
dc.contributor.authorO'Neill, S.en_US
dc.date.accessioned2017-04-24T13:05:21Z
dc.date.available2017-04-24T13:05:21Z
dc.date.issued2010en_US
dc.date.modified2011-02-14T09:14:13Z
dc.identifier.issn13652583en_US
dc.identifier.doi10.1111/j.1365-2583.2010.01042.xen_AU
dc.identifier.urihttp://hdl.handle.net/10072/36169
dc.description.abstractWolbachia are inherited intracellular bacteria that infect a broad range of invertebrate hosts. They commonly manipulate host reproduction in a variety of ways and thereby favour their invasion into host populations. While the biology of Wolbachia has been extensively studied at the ecological and phenotypic level, little is known about the molecular mechanisms underlying the interaction between Wolbachia and their hosts. Recent comparative genomics studies of Wolbachia strains have revealed putative candidate genes involved in the expression of cytoplasmic incompatibility (CI) in insects. However the functional testing of these genes is hindered by the lack of available genetic tools in Wolbachia. To circumvent this problem we generated transgenic Drosophila lines expressing various Wolbachia CI candidate genes under the control of the GAL4/UAS system in order to evaluate their possible role in Wolbachia-related phenotypes in Drosophila. The expression of a number of these genes in Drosophila melanogaster failed to mimic or alter CI phenotypes across a range of Wolbachia backgrounds or in the absence of Wolbachia.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherWiley-Blackwellen_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom75en_US
dc.relation.ispartofpageto85en_US
dc.relation.ispartofissue1en_US
dc.relation.ispartofjournalInsect Molecular Biologyen_US
dc.relation.ispartofvolume20en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchInfectious Agentsen_US
dc.subject.fieldofresearchcode060502en_US
dc.titleFunctional test of the influence of Wolbachia genes on cytoplasmic incompatibility expression in Drosophila melanogasteren_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2010
gro.hasfulltextNo Full Text


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