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dc.contributor.authorNoguchi, Shuhei
dc.contributor.authorArakawa, Takahiro
dc.contributor.authorFukuda, Shiro
dc.contributor.authorFuruno, Masaaki
dc.contributor.authorHasegawa, Akira
dc.contributor.authorHori, Fumi
dc.contributor.authorIshikawa-Kato, Sachi
dc.contributor.authorKaida, Kaoru
dc.contributor.authorKaiho, Ai
dc.contributor.authorKanamori-Katayama, Mutsumi
dc.contributor.authorKawashima, Tsugumi
dc.contributor.authorKojima, Miki
dc.contributor.authorKubosaki, Atsutaka
dc.contributor.authorManabe, Ri-ichiroh
dc.contributor.authorMurata, Mitsuyoshi
dc.contributor.authorNagao-Sato, Sayaka
dc.contributor.authorNakazato, Kenichi
dc.contributor.authorNinomiya, Noriko
dc.contributor.authorNishiyori-Sueki, Hiromi
dc.contributor.authorNoma, Shohei
dc.contributor.authorSaijyo, Eri
dc.contributor.authorSaka, Akiko
dc.contributor.authorSakai, Mizuho
dc.contributor.authorSimon, Christophe
dc.contributor.authorSuzuki, Naoko
dc.contributor.authorTagami, Michihira
dc.contributor.authorWatanabe, Shoko
dc.contributor.authorYoshida, Shigehiro
dc.contributor.authorArner, Peter
dc.contributor.authorAxton, Richard A
dc.contributor.authorBabina, Magda
dc.contributor.authorBaillie, J Kenneth
dc.contributor.authorBarnett, Timothy C
dc.contributor.authorBeckhouse, Anthony G
dc.contributor.authorBlumenthal, Antje
dc.contributor.authorBodega, Beatrice
dc.contributor.authorBonetti, Alessandro
dc.contributor.authorBriggs, James
dc.contributor.authorBrombacher, Frank
dc.contributor.authorCarlisle, Ailsa J
dc.contributor.authorClevers, Hans C
dc.contributor.authorDavis, Carrie A
dc.contributor.authorDetmar, Michael
dc.contributor.authorDohi, Taeko
dc.contributor.authorEdge, Albert SB
dc.contributor.authorEdinger, Matthias
dc.contributor.authorEhrlund, Anna
dc.contributor.authorEkwall, Karl
dc.contributor.authorEndoh, Mitsuhiro
dc.contributor.authorEnomoto, Hideki
dc.contributor.authorEslami, Afsaneh
dc.contributor.authorFagiolini, Michela
dc.contributor.authorFairbairn, Lynsey
dc.contributor.authorFarach-Carson, Mary C
dc.contributor.authorFaulkner, Geoffrey J
dc.contributor.authorFerrai, Carmelo
dc.contributor.authorFisher, Malcolm E
dc.contributor.authorForrester, Lesley M
dc.contributor.authorFujita, Rie
dc.contributor.authorFurusawa, Jun-ichi
dc.contributor.authorGeijtenbeek, Teunis B
dc.contributor.authorGingeras, Thomas
dc.contributor.authorGoldowitz, Daniel
dc.contributor.authorGuhl, Sven
dc.contributor.authorGuler, Reto
dc.contributor.authorGustincich, Stefano
dc.contributor.authorHa, Thomas J
dc.contributor.authorHamaguchi, Masahide
dc.contributor.authorHara, Mitsuko
dc.contributor.authorHasegawa, Yuki
dc.contributor.authorHerlyn, Meenhard
dc.contributor.authorHeutink, Peter
dc.contributor.authorHitchens, Kelly J
dc.contributor.authorHume, David A
dc.contributor.authorIkawa, Tomokatsu
dc.contributor.authorIshizu, Yuri
dc.contributor.authorKai, Chieko
dc.contributor.authorKawamoto, Hiroshi
dc.contributor.authorKawamura, Yuki I
dc.contributor.authorKempfle, Judith S
dc.contributor.authorKenna, Tony J
dc.contributor.authorKere, Juha
dc.contributor.authorKhachigian, Levon M
dc.contributor.authorKitamura, Toshio
dc.contributor.authorKlein, Sarah
dc.contributor.authorKlinken, S Peter
dc.contributor.authorKnox, Alan J
dc.contributor.authorKojima, Soichi
dc.contributor.authorKoseki, Haruhiko
dc.contributor.authorKoyasu, Shigeo
dc.contributor.authorLee, Weonju
dc.contributor.authorLennartsson, Andreas
dc.contributor.authorMackay-sim, Alan
dc.contributor.authorMejhert, Niklas
dc.contributor.authorMizuno, Yosuke
dc.contributor.authorMorikawa, Hiromasa
dc.contributor.authorMorimoto, Mitsuru
dc.contributor.authorMoro, Kazuyo
dc.contributor.authorMorris, Kelly J
dc.contributor.authorMotohashi, Hozumi
dc.contributor.authorMummery, Christine L
dc.contributor.authorNakachi, Yutaka
dc.contributor.authorNakahara, Fumio
dc.contributor.authorNakamura, Toshiyuki
dc.contributor.authorNakamura, Yukio
dc.contributor.authorNozaki, Tadasuke
dc.contributor.authorOgishima, Soichi
dc.contributor.authorOhkura, Naganari
dc.contributor.authorOhno, Hiroshi
dc.contributor.authorOhshima, Mitsuhiro
dc.contributor.authorOkada-Hatakeyama, Mariko
dc.contributor.authorOkazaki, Yasushi
dc.contributor.authorOrlando, Valerio
dc.contributor.authorOvchinnikov, Dmitry A
dc.contributor.authorPassier, Robert
dc.contributor.authorPatrikakis, Margaret
dc.contributor.authorPombo, Ana
dc.contributor.authorPradhan-Bhatt, Swati
dc.contributor.authorQin, Xian-Yang
dc.contributor.authorRehli, Michael
dc.contributor.authorRizzu, Patrizia
dc.contributor.authorRoy, Sugata
dc.contributor.authorSajantila, Antti
dc.contributor.authorSakaguchi, Shimon
dc.contributor.authorSato, Hiroki
dc.contributor.authorSatoh, Hironori
dc.contributor.authorSavvi, Suzana
dc.contributor.authorSaxena, Alka
dc.contributor.authorSchmidl, Christian
dc.contributor.authorSchneider, Claudio
dc.contributor.authorSchulze-Tanzil, Gundula G
dc.contributor.authorSchwegmann, Anita
dc.contributor.authorSheng, Guojun
dc.contributor.authorShin, Jay W
dc.contributor.authorSugiyama, Daisuke
dc.contributor.authorSugiyama, Takaaki
dc.contributor.authorSummers, Kim M
dc.contributor.authorTakahashi, Naoko
dc.contributor.authorTakai, Jun
dc.contributor.authorTanaka, Hiroshi
dc.contributor.authorTatsukawa, Hideki
dc.contributor.authorTomoiu, Andru
dc.contributor.authorToyoda, Hiroo
dc.contributor.authorvan de Wetering, Marc
dc.contributor.authorvan den Berg, Linda M
dc.contributor.authorVerardo, Roberto
dc.contributor.authorVijayan, Dipti
dc.contributor.authorWells, Christine A
dc.contributor.authorWinteringham, Louise N
dc.contributor.authorWolvetang, Ernst
dc.contributor.authorYamaguchi, Yoko
dc.contributor.authorYamamoto, Masayuki
dc.contributor.authorYanagi-Mizuochi, Chiyo
dc.contributor.authorYoneda, Misako
dc.contributor.authorYonekura, Yohei
dc.contributor.authorZhang, Peter G
dc.contributor.authorZucchelli, Silvia
dc.contributor.authorAbugessaisa, Imad
dc.contributor.authorArner, Erik
dc.contributor.authorHarshbarger, Jayson
dc.contributor.authorKondo, Atsushi
dc.contributor.authorLassmann, Timo
dc.contributor.authorLizio, Marina
dc.contributor.authorSahin, Serkan
dc.contributor.authorSengstag, Thierry
dc.contributor.authorSeverin, Jessica
dc.contributor.authorShimoji, Hisashi
dc.contributor.authorSuzuki, Masanori
dc.contributor.authorSuzuki, Harukazu
dc.contributor.authorKawai, Jun
dc.contributor.authorKondo, Naoto
dc.contributor.authorItoh, Masayoshi
dc.contributor.authorDaub, Carsten O
dc.contributor.authorKasukawa, Takeya
dc.contributor.authorKawaji, Hideya
dc.contributor.authorCarninci, Piero
dc.contributor.authorForrest, Alistair RR
dc.contributor.authorHayashizaki, Yoshihide
dc.date.accessioned2018-01-17T22:56:34Z
dc.date.available2018-01-17T22:56:34Z
dc.date.issued2017
dc.identifier.issn2052-4463
dc.identifier.doi10.1038/sdata.2017.112
dc.identifier.urihttp://hdl.handle.net/10072/364235
dc.description.abstractIn the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGE data production. The analysis pipeline started by measuring RNA extracts to assess their quality, and continued to CAGE library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGE profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherNature Publishing Group
dc.relation.ispartofpagefrom170112-1
dc.relation.ispartofpageto170112-10
dc.relation.ispartofjournalScientific Data
dc.relation.ispartofvolume4
dc.subject.fieldofresearchBioinformatics
dc.subject.fieldofresearchcode060102
dc.titleFANTOM5 CAGE profiles of human and mouse samples
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons. org/licenses/by/4.0/
dc.description.versionPublished
gro.rights.copyright© The Author(s) 2017. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/
gro.hasfulltextFull Text
gro.griffith.authorMackay-Sim, Alan
gro.griffith.authorWells, Christine
gro.griffith.authorForrest, Alistair RR.
gro.griffith.authorBeckhouse, Anthony G.


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