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dc.contributor.advisorKorolik, Victoria
dc.contributor.authorShewell, Lucy
dc.date.accessioned2018-01-23T02:18:23Z
dc.date.available2018-01-23T02:18:23Z
dc.date.issued2011
dc.identifier.doi10.25904/1912/496
dc.identifier.urihttp://hdl.handle.net/10072/365435
dc.description.abstractCampylobacter jejuni colonizes the intestinal mucosa of all food-producing animals and humans (Newell & Fearnley, 2003) and is the leading cause of human bacterial gastroenteritis worldwide (Blaser, 1997; Friedman et al., 2000). It is unclear exactly how C. jejuni induces disease outcome in humans, however, a number of factors have been implicated in the pathogenesis of this organism, including colonization and adherence, invasion and translocation, toxin production, LOS and capsule structures, flagella and motility, protein glycosylation and chemotaxis. Chemotactic behaviour has been demonstrated in C. jejuni (Hugdahl et al., 1988) and previous studies have shown the importance of chemotactic motility to the ability of C. jejuni to colonize and cause disease (Takata et al., 1992; Yao et al., 1997). However, the mechanisms controlling the C. jejuni chemotaxis signalling pathway remain largely unknown.
dc.languageEnglish
dc.publisherGriffith University
dc.publisher.placeBrisbane
dc.rights.copyrightThe author owns the copyright in this thesis, unless stated otherwise.
dc.subject.keywordsCampylobacter jejuni
dc.subject.keywordsBacterial gastoenteritis
dc.subject.keywordsChemotaxis
dc.titleCharacterisation of the Chemotaxis Signalling Pathway of Campylobacter Jejuni
dc.typeGriffith thesis
gro.facultyScience, Environment, Engineering and Technology
gro.description.notepublicThis thesis has been scanned. The published article included as pages 248-268 has not been published here for copyright reasons.
gro.rights.copyrightThe author owns the copyright in this thesis, unless stated otherwise.
gro.hasfulltextFull Text
dc.contributor.otheradvisorBeacham, Ifor
dc.rights.accessRightsPublic
gro.identifier.gurtIDgu1358396678322
gro.source.ADTshelfnoADT0
gro.source.GURTshelfnoGURT1375
gro.thesis.degreelevelThesis (PhD Doctorate)
gro.thesis.degreeprogramDoctor of Philosophy (PhD)
gro.departmentInstitute for Glycomics
gro.griffith.authorShewell, Lucy K.


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