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  • Phytochemical Study and Anticancer Potential of High Antioxidant Australian Native Plants

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    Sirdaarta_2016_01Thesis.pdf (7.344Mb)
    Author(s)
    P, Joseph S.
    Primary Supervisor
    Cock, Ian
    Other Supervisors
    Ashmore, Sarah
    Year published
    2016
    Metadata
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    Abstract
    High antioxidant capacities have been linked with a reduction in the incidence of chronic diseases including cardiovascular disease, diabetes, obesity, neurodegeneration, inflammation and cancer. Furthermore, phenolic antioxidants may not only have protective effects against these diseases, but may also have therapeutic potential in reversing them by modulation of the cellular redox state. Thus, plants with high antioxidant capacities have potential in the development of new chemotherapeutic treatments to prevent and treat some cancers. Several native Australian plant species including Terminalia ferdinandiana Exell (Kakadu ...
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    High antioxidant capacities have been linked with a reduction in the incidence of chronic diseases including cardiovascular disease, diabetes, obesity, neurodegeneration, inflammation and cancer. Furthermore, phenolic antioxidants may not only have protective effects against these diseases, but may also have therapeutic potential in reversing them by modulation of the cellular redox state. Thus, plants with high antioxidant capacities have potential in the development of new chemotherapeutic treatments to prevent and treat some cancers. Several native Australian plant species including Terminalia ferdinandiana Exell (Kakadu plum), Tasmannia lanceolata (Poir.) A.C.Sm., (Tasmannian pepper), Syzygium australe (H.L.Wendl. ex Link) B.Hyland (brush cherry), Syzygium luehmannii (F.Muell.) L.A.S.Johnson (riberry), Davidsonia pruriens F.Muell. (Davidson’s plum), Elaeocarpus angustifolius Blume (quandong), Kunzea pomifera F.Muell. (muntries), Podocarpus elatus R.Br.ex Endl., (Illawarra plum) and Acronychia acidula F.Muell., (lemon aspen) have recently been reported to have extraordinarily high antioxidant content and were therefore selected to screen for the ability to inhibit proliferation of selected carcinoma cell lines.
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    Thesis Type
    Thesis (PhD Doctorate)
    Degree Program
    Doctor of Philosophy (PhD)
    School
    School of Natural Sciences
    DOI
    https://doi.org/10.25904/1912/1565
    Copyright Statement
    The author owns the copyright in this thesis, unless stated otherwise.
    Item Access Status
    Public
    Subject
    Medicinal plants
    Antioxidant Australian Native Plants
    Anticancer herbs
    Phenolic antioxidants
    Publication URI
    http://hdl.handle.net/10072/365567
    Collection
    • Theses - Higher Degree by Research

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