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dc.contributor.advisorMohd-Yasin, Faisal
dc.contributor.authorKhaw, Mei Kum
dc.date.accessioned2018-01-23T02:24:10Z
dc.date.available2018-01-23T02:24:10Z
dc.date.issued2017
dc.identifier.doi10.25904/1912/1837
dc.identifier.urihttp://hdl.handle.net/10072/365947
dc.description.abstractDigital microfluidic is an emerging liquid handling technique where discrete droplets are manipulated on a substrate. For the past decades, conventional microfluidic applications are based on continuous flow concept. They require complicated networks of channels, pumps and valves to manage the flow of droplets in microchannels. In digital microfluidics, droplets are moved individually on an open surface. The droplets have the flexibility to move in various directions, making a single device flexible for diverse reaction designs and applications. The manipulation of discrete droplets allows reduction in sample size, faster heat transfer and reaction rates and easier collection of samples. The droplets can be manipulated via electrostatic force, magnetic force, gravitational force, pressure gradient, pH change, surfactant concentration, temperature change, Marangoni propulsion and light-induced surface tension gradient. Magnetic actuation is an excellent candidate for digital microfluidic applications because of the simplicity of using external magnetic field for a non-contact and non-invasive control over magnetised droplets. The magnetic field can penetrate through substrates and biological materials. There is also a wide variety of available magnetic particles and it is easy to control the amount of magnetic particles loaded into the carrier liquid. Some magnetic particles can absorb nucleic acids and other biomolecules making it possible for biomolecular separation. Magnetic manipulation is not affected by factors such as surface charges, pH and ion concentration. In most cases, magnetic manipulation does not induce heating.
dc.languageEnglish
dc.publisherGriffith University
dc.publisher.placeBrisbane
dc.rights.copyrightThe author owns the copyright in this thesis, unless stated otherwise.
dc.subject.keywordsDigital microfluidic
dc.subject.keywordsLiquid handling technique
dc.subject.keywordsMagnetically actuated droplets
dc.subject.keywordsMarangoni propulsion
dc.subject.keywordsMagnetic actuation
dc.subject.keywordsMagnetic particles
dc.titleStudies on Magnetically Actuated Droplets for Digital Microfluidic
dc.typeGriffith thesis
gro.facultyScience, Environment, Engineering and Technology
gro.rights.copyrightThe author owns the copyright in this thesis, unless stated otherwise.
gro.hasfulltextFull Text
dc.contributor.otheradvisorNguyen, Nam-Trung
dc.rights.accessRightsPublic
gro.identifier.gurtIDgu1504672395794
gro.thesis.degreelevelThesis (PhD Doctorate)
gro.thesis.degreeprogramDoctor of Philosophy (PhD)
gro.departmentGriffith School of Engineering
gro.griffith.authorKhaw, Mei Kum K.


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