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dc.contributor.authorYin, Shengen_US
dc.contributor.authorM. Boyle, Glenen_US
dc.contributor.authorCarroll, Anthonyen_US
dc.contributor.authorKotiw, Michaelen_US
dc.contributor.authorDearnaley, Johnen_US
dc.contributor.authorQuinn, Ronalden_US
dc.contributor.authorDavis, Rohanen_US
dc.date.accessioned2017-05-03T12:46:44Z
dc.date.available2017-05-03T12:46:44Z
dc.date.issued2010en_US
dc.identifier.issn0163-3864en_US
dc.identifier.doi10.1021/np100329wen_US
dc.identifier.urihttp://hdl.handle.net/10072/36773
dc.description.abstractFour new brominated natural products, caelestines A-D (1-4), have been isolated from the Australian ascidian Aplidium caelestis. The structures of 1-4 were determined by analysis of their NMR and MS data. This is the first report of brominated quinolinecarboxylic acids from nature. Compound 1 has been previously synthesized but not spectroscopically characterized. Compounds 1-4 were tested against three mammalian cell lines (MCF-7, NFF, and MM96L) and a panel of microbial strains and showed only minor cytotoxicity.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_US
dc.format.extent160262 bytes
dc.format.mimetypeapplication/pdf
dc.languageEnglishen_US
dc.language.isoen_US
dc.publisherAmerican Chemical Societyen_US
dc.publisher.placeUnited Statesen_US
dc.relation.ispartofstudentpublicationNen_US
dc.relation.ispartofpagefrom1586en_US
dc.relation.ispartofpageto1589en_US
dc.relation.ispartofissue9en_US
dc.relation.ispartofjournalJournal of Natural Productsen_US
dc.relation.ispartofvolume73en_US
dc.rights.retentionNen_US
dc.subject.fieldofresearchNatural Products Chemistryen_US
dc.subject.fieldofresearchcode030502en_US
dc.titleCaelestines A-D, brominated quinolinecarboxylic acids from the Australian ascidian aplidium caelestisen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.facultyGriffith Sciences, Griffith Institute for Drug Discoveryen_US
gro.rights.copyrightThis document is the Accepted Manuscript version of a Published Work that appeared in final form in the Journal of Natural Products, copyright 2010 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np100329w.en_US
gro.date.issued2015-07-30T23:08:55Z
gro.hasfulltextFull Text


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