Evidence of depression-associated circadian rhythm disruption and regret in prostate cancer patients after surgery
Author(s)
Christie, Joanne
Sharpley, Christopher F.
Bitsika, Vicki
Christie, David
Griffith University Author(s)
Year published
2017
Metadata
Show full item recordAbstract
Purpose:
The purpose of this study is to investigate the association between prostate cancer (PCa) patients’ regret that their surgery harmed them, and their scores on the two key symptoms of major depressive disorder (depressed mood, anhedonia) and a symptom of melancholic depression (disruption to circadian rhythm).
Methods:
Forty PCa patients who had received surgery for their PCa completed a postal survey including background information, regret about surgery that ‘did them a lot of harm’ and three items drawn from the Zung Self-Rating Depression Scale measuring depressed mood, anhedonia and circadian rhythm ...
View more >Purpose: The purpose of this study is to investigate the association between prostate cancer (PCa) patients’ regret that their surgery harmed them, and their scores on the two key symptoms of major depressive disorder (depressed mood, anhedonia) and a symptom of melancholic depression (disruption to circadian rhythm). Methods: Forty PCa patients who had received surgery for their PCa completed a postal survey including background information, regret about surgery that ‘did them a lot of harm’ and three items drawn from the Zung Self-Rating Depression Scale measuring depressed mood, anhedonia and circadian rhythm disruption. Results: There were significant correlations between all three symptoms of depression (depressed mood, anhedonia, disruption to circadian rhythm) and between patients’ regret that surgery did them a lot of harm and their circadian rhythm disruption, but not between depressed mood or anhedonia and regret about surgery doing harm. Conclusions: These findings suggest that PCa patients’ post-surgery regrets about major harm may lead to a significant disruption in a central physiological function and raise the need to consider this side effect of surgery when planning supportive services for these men.
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View more >Purpose: The purpose of this study is to investigate the association between prostate cancer (PCa) patients’ regret that their surgery harmed them, and their scores on the two key symptoms of major depressive disorder (depressed mood, anhedonia) and a symptom of melancholic depression (disruption to circadian rhythm). Methods: Forty PCa patients who had received surgery for their PCa completed a postal survey including background information, regret about surgery that ‘did them a lot of harm’ and three items drawn from the Zung Self-Rating Depression Scale measuring depressed mood, anhedonia and circadian rhythm disruption. Results: There were significant correlations between all three symptoms of depression (depressed mood, anhedonia, disruption to circadian rhythm) and between patients’ regret that surgery did them a lot of harm and their circadian rhythm disruption, but not between depressed mood or anhedonia and regret about surgery doing harm. Conclusions: These findings suggest that PCa patients’ post-surgery regrets about major harm may lead to a significant disruption in a central physiological function and raise the need to consider this side effect of surgery when planning supportive services for these men.
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Journal Title
Supportive Care in Cancer
Volume
25
Issue
12
Subject
Oncology and Carcinogenesis not elsewhere classified
Medical and Health Sciences
Psychology and Cognitive Sciences