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dc.contributor.authorSiddiqui, Khawar Sohail
dc.contributor.authorShemsi, Ahsan Mushir
dc.contributor.authorGuerriero, Gea
dc.contributor.authorNajnin, Tahria
dc.contributor.authorTaha
dc.contributor.authorErtan, Haluk
dc.contributor.editorRosa Margesin
dc.date.accessioned2018-10-12T01:34:36Z
dc.date.available2018-10-12T01:34:36Z
dc.date.issued2017
dc.identifier.isbn9783319570563
dc.identifier.doi10.1007/978-3-319-57057-0_20
dc.identifier.urihttp://hdl.handle.net/10072/369059
dc.description.abstractCold-adapted (psychrophilic) enzymes have intrinsically high activities at the expense of low stabilities due to their flexible structures. Their higher thermolability limits their applications under numerous industrial conditions that require the process to be carried out at higher temperatures for efficient catalysis. Therefore, for effective utilization, cold-adapted enzymes need to be improved in such a way that enhances their stability with an increase or retention of their activity. This chapter discusses the thermodynamic aspects of improvement of catalytic properties and presents a unified strategy that aims at simultaneously improving the activity and stability of cold-adapted enzymes by employing not a single but a combination of approaches that include genetic and chemical modifications, immobilization, nonaqueous solvents, and additives. This concept aims to take cold-adapted enzymes a step further from current potential to cost-effective tangible commercial applications.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer International Publishing
dc.publisher.placeSwitzerland
dc.relation.ispartofbooktitlePsychrophiles: From Biodiversity to Biotechnology
dc.relation.ispartofchapter20
dc.relation.ispartofpagefrom477
dc.relation.ispartofpageto512
dc.subject.fieldofresearchMedical Biotechnology not elsewhere classified
dc.subject.fieldofresearchcode100499
dc.titleBiotechnological Improvements of Cold-Adapted Enzymes: Commercialization via an Integrated Approach
dc.typeBook chapter
dc.type.descriptionB1 - Chapters
dc.type.codeB - Book Chapters
gro.hasfulltextNo Full Text
gro.griffith.authorNajnin, Tahria
gro.griffith.authorTaha, .


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