Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device
Author(s)
Teo, Adrian JT
Li, King-Ho Holden
Nam-Trung, Nguyen
Guo, Wei
Heere, Nadine
Xi, Heng-Dong
Tsao, Chia-Wen
Li, Weihua
Tan, Say Hwa
Year published
2017
Metadata
Show full item recordAbstract
We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.
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Journal Title
Analytical Chemistry
Volume
89
Subject
Analytical chemistry
Other chemical sciences
Mechanical engineering not elsewhere classified
Medical biochemistry and metabolomics
Chemical engineering