Show simple item record

dc.contributor.authorAlrawahi, Abdul Hakeem
dc.contributor.authorLee, Patricia
dc.date.accessioned2019-05-29T12:32:09Z
dc.date.available2019-05-29T12:32:09Z
dc.date.issued2018
dc.identifier.issn1871-4021
dc.identifier.doi10.1016/j.dsx.2018.01.004
dc.identifier.urihttp://hdl.handle.net/10072/371553
dc.description.abstractAim: The first cardiovascular risk prediction model in the Arab world was recently developed for Omanis with type 2 diabetes mellitus. This study aims to validate the newly developed model. Materials and methods: A retrospective cohort study design was applied in this study. The model was validated in two samples; the model derivation sample and a separate validation sample, consisting of 1314 and 405 diabetics respectively. All patients were free of cardiovascular disease at the baseline (2009–2010) and were followed up until: the first cardiovascular event occurred; the patient died; or up to December 2015. All data were retrieved from the patients’ medical records in a primary care setting. Results: In both the derivation and validation samples, the model showed good discrimination, with an area under the receiver operating curve of 0.73 (95% CI; 0.69–0.77) and 0.70 (95% CI: 0.59–0.75) respectively. Calibration of the model was satisfactory and the actual difference between the mean predicted and observed risk in different risk groups ranged from 0.7%–3.1% and 0.1%–4.2% in the derivation and validation samples respectively. Conclusion: The recently developed cardiovascular disease risk assessment model for Omanis with type 2 diabetes achieved adequate overall validity. The model showed good discrimination and acceptable calibration; it therefore has the potential to be used in local clinical settings. However, further validation and comparison studies are needed to judge the generalizability and superiority of the model over other tools currently used in Oman.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherElsevier
dc.publisher.placeUnited States
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto5
dc.relation.ispartofjournalDiabetes & Metabolic Syndrome: Clinical Research & Review
dc.subject.fieldofresearchEpidemiology
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode111706
dc.subject.fieldofresearchcode1103
dc.titleValidation of the cardiovascular risk model developed for Omanis with type 2 diabetes
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Health, School of Medicine
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version.
gro.hasfulltextNo Full Text
gro.griffith.authorLee, Patricia T.
gro.griffith.authorAl Rawahi, Abdul Hakeem H.


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record