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dc.contributor.authorVos, Theo
dc.contributor.authorAbajobir, Amanuel Alemu
dc.contributor.authorAbbafati, Cristiana
dc.contributor.authorAbbas, Kaja M
dc.contributor.authorAbate, Kalkidan Hassen
dc.contributor.authorAbd-Allah, Foad
dc.contributor.authorAbdulle, Abdishakur M
dc.contributor.authorAbebo, Teshome Abuka
dc.contributor.authorAbera, Semaw Ferede
dc.contributor.authorAboyans, Victor
dc.contributor.authorAbu-Raddad, Laith J
dc.contributor.authorAckerman, Ilana N
dc.contributor.authorAdamu, Abdu Abdullahi
dc.contributor.authorAdetokunboh, Olatunji
dc.contributor.authorAfarideh, Mohsen
dc.contributor.authorAfshin, Ashkan
dc.contributor.authorAgarwal, Sanjay Kumar
dc.contributor.authorAggarwal, Rakesh
dc.contributor.authorAgrawal, Anurag
dc.contributor.authorAgrawal, Sutapa
dc.contributor.authorKiadaliri, Aliasghar Ahmad
dc.contributor.authorAhmadieh, Hamid
dc.contributor.authorAhmed, Muktar Beshir
dc.contributor.authorAichour, Amani Nidhal
dc.contributor.authorAichour, Ibtihel
dc.contributor.authorAichour, Miloud Taki Eddine
dc.contributor.authorAiyar, Sneha
dc.contributor.authorAkinyemi, Rufus Olusola
dc.contributor.authorAkseer, Nadia
dc.contributor.authorAl Lami, Faris Hasan
dc.contributor.authorAlahdab, Fares
dc.contributor.authorAl-Aly, Ziyad
dc.contributor.authorAlam, Khurshid
dc.contributor.authorAlam, Noore
dc.contributor.authorAlam, Tahiya
dc.contributor.authorAlasfoor, Deena
dc.contributor.authorAlene, Kefyalew Addis
dc.contributor.authorAli, Raghib
dc.contributor.authorAlizadeh-Navaei, Reza
dc.contributor.authorAlkerwi, Ala'a
dc.contributor.authorAlla, Francois
dc.contributor.authorAllebeck, Peter
dc.contributor.authorAllen, Christine
dc.contributor.authorAl-Maskari, Fatma
dc.contributor.authorAl-Raddadi, Rajaa
dc.contributor.authorAlsharif, Ubai
dc.contributor.authorAlsowaidi, Shirina
dc.contributor.authorAltirkawi, Khalid A
dc.contributor.authorAmare, Azmeraw T
dc.contributor.authorAmini, Erfan
dc.contributor.authorAmmar, Walid
dc.contributor.authorAmoako, Yaw Ampem
dc.contributor.authorAndersen, Hjalte H
dc.contributor.authorAntonio, Carl Abelardo T
dc.contributor.authorAnwari, Palwasha
dc.contributor.authorArnlov, Johan
dc.contributor.authorArtaman, Al
dc.contributor.authorAryal, Krishna Kumar
dc.contributor.authorAsayesh, Hamid
dc.contributor.authorAsgedom, Solomon W
dc.contributor.authorAssadi, Reza
dc.contributor.authorAtey, Tesfay Mehari
dc.contributor.authorAtnafu, Niguse Tadele
dc.contributor.authorAtre, Sachin R
dc.contributor.authorAvila-Burgos, Leticia
dc.contributor.authorAvokpaho, Euripide Frinel G Arthur
dc.contributor.authorAwasthi, Ashish
dc.contributor.authorAyala Quintanilla, Beatriz Paulina
dc.contributor.authorSaleem, Huda Omer Ba
dc.contributor.authorBacha, Umar
dc.contributor.authorBadawi, Alaa
dc.contributor.authorBalakrishnan, Kalpana
dc.contributor.authorBanerjee, Amitava
dc.contributor.authorBannick, Marlena S
dc.contributor.authorBarac, Aleksandra
dc.contributor.authorBarber, Ryan M
dc.contributor.authorBarker-Collo, Suzanne L
dc.contributor.authorBaernighausen, Till
dc.contributor.authorBarquera, Simon
dc.contributor.authorBarregard, Lars
dc.contributor.authorBarrero, Lope H
dc.contributor.authorBasu, Sanjay
dc.contributor.authorBattista, Bob
dc.contributor.authorBattle, Katherine E
dc.contributor.authorBaune, Bernhard T
dc.contributor.authorBazargan-Hejazi, Shahrzad
dc.contributor.authorBeardsley, Justin
dc.contributor.authorBedi, Neeraj
dc.contributor.authorBeghi, Ettore
dc.contributor.authorBejot, Yannick
dc.contributor.authorBekele, Bayu Begashaw
dc.contributor.authorBell, Michelle L
dc.contributor.authorBennett, Derrick A
dc.contributor.authorBensenor, Isabela M
dc.contributor.authorBenson, Jennifer
dc.contributor.authorBerhane, Adugnaw
dc.contributor.authorBerhe, Derbew Fikadu
dc.contributor.authorBernabe, Eduardo
dc.contributor.authorBetsu, Balem Demtsu
dc.contributor.authorBeuran, Mircea
dc.contributor.authorBeyene, Addisu Shunu
dc.contributor.authorBhala, Neeraj
dc.contributor.authorBhansali, Anil
dc.contributor.authorBhatt, Samir
dc.contributor.authorBhutta, Zulfiqar A
dc.contributor.authorBiadgilign, Sibhatu
dc.contributor.authorBienhoff, Kelly
dc.contributor.authorBikbov, Boris
dc.contributor.authorBirungi, Charles
dc.contributor.authorBiryukov, Stan
dc.contributor.authorBisanzio, Donal
dc.contributor.authorBizuayehu, Habtamu Mellie
dc.contributor.authorBoneya, Dube Jara
dc.contributor.authorBoufous, Soufiane
dc.contributor.authorBourne, Rupert RA
dc.contributor.authorBrazinova, Alexandra
dc.contributor.authorBrugha, Traolach S
dc.contributor.authorBuchbinder, Rachelle
dc.contributor.authorBulto, Lemma Negesa Bulto
dc.contributor.authorBumgarner, Blair R
dc.contributor.authorButt, Zahid A
dc.contributor.authorCahuana-Hurtado, Lucero
dc.contributor.authorCameron, Ewan
dc.contributor.authorCar, Mate
dc.contributor.authorCarabin, Helene
dc.contributor.authorCarapetis, Jonathan R
dc.contributor.authorCardenas, Rosario
dc.contributor.authorCarpenter, David O
dc.contributor.authorCarrero, Juan Jesus
dc.contributor.authorCarter, Austin
dc.contributor.authorCarvalho, Felix
dc.contributor.authorCasey, Daniel C
dc.contributor.authorCaso, Valeria
dc.contributor.authorCastaneda-Orjuela, Carlos A
dc.contributor.authorCastle, Chris D
dc.contributor.authorCatala-Lopez, Ferran
dc.contributor.authorChang, Hsing-Yi
dc.contributor.authorChang, Jung-Chen
dc.contributor.authorCharlson, Fiona J
dc.contributor.authorChen, Honglei
dc.contributor.authorChibalabala, Mirriam
dc.contributor.authorChibueze, Chioma Ezinne
dc.contributor.authorChisumpa, Vesper Hichilombwe
dc.contributor.authorChitheer, Abdulaal A
dc.contributor.authorChristopher, Devasahayam Jesudas
dc.contributor.authorCiobanu, Liliana G
dc.contributor.authorCirillo, Massimo
dc.contributor.authorColombara, Danny
dc.contributor.authorCooper, Cyrus
dc.contributor.authorCortesi, Paolo Angelo
dc.contributor.authorCriqui, Michael H
dc.contributor.authorCrump, John A
dc.contributor.authorDadi, Abel Fekadu
dc.contributor.authorDalal, Koustuv
dc.contributor.authorDandona, Lalit
dc.contributor.authorDandona, Rakhi
dc.contributor.authordas Neves, Jose
dc.contributor.authorDavitoiu, Dragos V
dc.contributor.authorde Courten, Barbora
dc.contributor.authorDe Leo, Diego
dc.contributor.authorDegenhardt, Louisa
dc.contributor.authorDeiparine, Selina
dc.contributor.authorDellavalle, Robert P
dc.contributor.authorDeribe, Kebede
dc.contributor.authorDes Jarlais, Don C
dc.contributor.authorDey, Subhojit
dc.contributor.authorDharmaratne, Samath D
dc.contributor.authorDhillon, Preet Kaur
dc.contributor.authorDicker, Daniel
dc.contributor.authorDing, Eric L
dc.contributor.authorDjalalinia, Shirin
dc.contributor.authorHuyen, Phuc Do
dc.contributor.authorDorsey, E Ray
dc.contributor.authorBender dos Santos, Kadine Priscila
dc.contributor.authorDouwes-Schultz, Dirk
dc.contributor.authorDoyle, Kerrie E
dc.contributor.authorDriscoll, Tim R
dc.contributor.authorDubey, Manisha
dc.contributor.authorDuncan, Bruce Bartholow
dc.contributor.authorEl-Khatib, Ziad Ziad
dc.contributor.authorEllerstrand, Jerisha
dc.contributor.authorEnayati, Ahmadali
dc.contributor.authorEndries, Aman Yesuf
dc.contributor.authorErmakov, Sergey Petrovich
dc.contributor.authorErskine, Holly E
dc.contributor.authorEshrati, Babak
dc.contributor.authorEskandarieh, Sharareh
dc.contributor.authorEsteghamati, Alireza
dc.contributor.authorEstep, Kara
dc.contributor.authorFanuel, Fanuel Belayneh Bekele
dc.contributor.authorSa Farinha, Carla Sofia E
dc.contributor.authorFaro, Andre
dc.contributor.authorFarzadfar, Farshad
dc.contributor.authorFazeli, Mir Sohail
dc.contributor.authorFeigin, Valery L
dc.contributor.authorFereshtehnejad, Seyed-Mohammad
dc.contributor.authorFernandes, Joao C
dc.contributor.authorFerrari, Alize J
dc.contributor.authorFeyissa, Tesfaye Regassa
dc.contributor.authorFilip, Irina
dc.contributor.authorFischer, Florian
dc.contributor.authorFitzmaurice, Christina
dc.contributor.authorFlaxman, Abraham D
dc.contributor.authorFlor, Luisa Sorio
dc.contributor.authorFoigt, Nataliya
dc.contributor.authorForeman, Kyle J
dc.contributor.authorFranklin, Richard C
dc.contributor.authorFullman, Nancy
dc.contributor.authorFurst, Thomas
dc.contributor.authorFurtado, Joao M
dc.contributor.authorFutran, Neal D
dc.contributor.authorGakidou, Emmanuela
dc.contributor.authorGanji, Morsaleh
dc.contributor.authorGarcia-Basteiro, Alberto L
dc.contributor.authorGebre, Teshome
dc.contributor.authorGebrehiwot, Tsegaye Tewelde
dc.contributor.authorGeleto, Ayele
dc.contributor.authorGemechu, Bikila Lencha
dc.contributor.authorGesesew, Hailay Abrha
dc.contributor.authorGething, Peter W
dc.contributor.authorGhajar, Alireza
dc.contributor.authorGibney, Katherine B
dc.contributor.authorGill, Paramjit Singh
dc.contributor.authorGillum, Richard F
dc.contributor.authorGinawi, Ibrahim Abdelmageem Mohamed
dc.contributor.authorGiref, Ababi Zergay
dc.contributor.authorGishu, Melkamu Dedefo
dc.contributor.authorGiussani, Giorgia
dc.contributor.authorGodwin, William W
dc.contributor.authorGold, Audra L
dc.contributor.authorGoldberg, Ellen M
dc.contributor.authorGona, Philimon N
dc.contributor.authorGoodridge, Amador
dc.contributor.authorGopalani, Sameer Vali
dc.contributor.authorGoto, Atsushi
dc.contributor.authorGoulart, Alessandra Carvalho
dc.contributor.authorGriswold, Max
dc.contributor.authorGugnani, Harish Chander
dc.contributor.authorGupta, Rahul
dc.contributor.authorGupta, Rajeev
dc.contributor.authorGupta, Tanush
dc.contributor.authorGupta, Vipin
dc.contributor.authorHafezi-Nejad, Nima
dc.contributor.authorHailu, Alemayehu Desalegne
dc.contributor.authorHailu, Gessessew Bugssa
dc.contributor.authorHamadeh, Randah Ribhi
dc.contributor.authorHamidi, Samer
dc.contributor.authorHandal, Alexis J
dc.contributor.authorHankey, Graeme J
dc.contributor.authorHao, Yuantao
dc.contributor.authorHarb, Hilda L
dc.contributor.authorHareri, Habtamu Abera
dc.contributor.authorMaria Haro, Josep
dc.contributor.authorHarvey, James
dc.contributor.authorHassanvand, Mohammad Sadegh
dc.contributor.authorHavmoeller, Rasmus
dc.contributor.authorHawley, Caitlin
dc.contributor.authorHay, Roderick J
dc.contributor.authorHay, Simon I
dc.contributor.authorHenry, Nathaniel J
dc.contributor.authorBeatriz Heredia-Pi, Ileana
dc.contributor.authorHeydarpour, Pouria
dc.contributor.authorHoek, Hans W
dc.contributor.authorHoffman, Howard J
dc.contributor.authorHorita, Nobuyuki
dc.contributor.authorHosgood, H Dean
dc.contributor.authorHostiuc, Sorin
dc.contributor.authorHotez, Peter J
dc.contributor.authorHoy, Damian G
dc.contributor.authorHtet, Aung Soe
dc.contributor.authorHu, Guoqing
dc.contributor.authorHuang, Hsiang
dc.contributor.authorHuynh, Chantal
dc.contributor.authorIburg, Kim Moesgaard
dc.contributor.authorIgumbor, Ehimario Uche
dc.contributor.authorIkeda, Chad
dc.contributor.authorIrvine, Caleb Mackay Salpeter
dc.contributor.authorJacobsen, Kathryn H
dc.contributor.authorJahanmehr, Nader
dc.contributor.authorJakovljevic, Mihajlo B
dc.contributor.authorJassal, Simerjot K
dc.contributor.authorJavanbakht, Mehdi
dc.contributor.authorJayaraman, Sudha P
dc.contributor.authorJeemon, Panniyammakal
dc.contributor.authorJensen, Paul N
dc.contributor.authorJha, Vivekanand
dc.contributor.authorJiang, Guohong
dc.contributor.authorJohn, Denny
dc.contributor.authorJohnson, Catherine O
dc.contributor.authorJohnson, Sarah Charlotte
dc.contributor.authorJonas, Jost B
dc.contributor.authorJurisson, Mikk
dc.contributor.authorKabir, Zubair
dc.contributor.authorKadel, Rajendra
dc.contributor.authorKahsay, Amaha
dc.contributor.authorKamal, Ritul
dc.contributor.authorKan, Haidong
dc.contributor.authorKaram, Nadim E
dc.contributor.authorKarch, Andre
dc.contributor.authorKarema, Corine Kakizi
dc.contributor.authorKasaeian, Amir
dc.contributor.authorKassa, Getachew Mullu
dc.contributor.authorKassaw, Nigussie Assefa
dc.contributor.authorKassebaum, Nicholas J
dc.contributor.authorKastor, Anshul
dc.contributor.authorKatikireddi, Srinivasa Vittal
dc.contributor.authorKaul, Anil
dc.contributor.authorKawakami, Norito
dc.contributor.authorKeiyoro, Peter Njenga
dc.contributor.authorKengne, Andre Pascal
dc.contributor.authorKeren, Andre
dc.contributor.authorKhader, Yousef Saleh
dc.contributor.authorKhalil, Ibrahim A
dc.contributor.authorKhan, Ejaz Ahmad
dc.contributor.authorKhang, Young-Ho
dc.contributor.authorKhosravi, Ardeshir
dc.contributor.authorKhubchandani, Jagdish
dc.contributor.authorKieling, Christian
dc.contributor.authorKim, Daniel
dc.contributor.authorKim, Pauline
dc.contributor.authorKim, Yun Jin
dc.contributor.authorKimokoti, Ruth W
dc.contributor.authorKinfu, Yohannes
dc.contributor.authorKisa, Adnan
dc.contributor.authorKissimova-Skarbek, Katarzyna A
dc.contributor.authorKivimaki, Mika
dc.contributor.authorKnudsen, Ann Kristin
dc.contributor.authorKokubo, Yoshihiro
dc.contributor.authorKolte, Dhaval
dc.contributor.authorKopec, Jacek A
dc.contributor.authorKosen, Soewarta
dc.contributor.authorKoul, Parvaiz A
dc.contributor.authorKoyanagi, Ai
dc.contributor.authorKravchenko, Michael
dc.contributor.authorKrishnaswami, Sanjay
dc.contributor.authorKrohn, Kristopher J
dc.contributor.authorDefo, Barthelemy Kuate
dc.contributor.authorBicer, Burcu Kucuk
dc.contributor.authorKumar, G Anil
dc.contributor.authorKumar, Pushpendra
dc.contributor.authorKumar, Sanjiv
dc.contributor.authorKyu, Hmwe H
dc.contributor.authorLal, Dharmesh Kumar
dc.contributor.authorLalloo, Ratilal
dc.contributor.authorLambert, Nkurunziza
dc.contributor.authorLan, Qing
dc.contributor.authorLarsson, Anders
dc.contributor.authorLavados, Pablo M
dc.contributor.authorLeasher, Janet L
dc.contributor.authorLee, Jong-Tae
dc.contributor.authorLee, Paul H
dc.contributor.authorLeigh, James
dc.contributor.authorLeshargie, Cheru Tesema
dc.contributor.authorLeung, Janni
dc.contributor.authorLeung, Ricky
dc.contributor.authorLevi, Miriam
dc.contributor.authorLi, Yichong
dc.contributor.authorLi, Yongmei
dc.contributor.authorLi Kappe, Darya
dc.contributor.authorLiang, Xiaofeng
dc.contributor.authorLiben, Misgan Legesse
dc.contributor.authorLim, Stephen S
dc.contributor.authorLinn, Shai
dc.contributor.authorLiu, Angela
dc.contributor.authorLiu, Patrick Y
dc.contributor.authorLiu, Shiwei
dc.contributor.authorLiu, Yang
dc.contributor.authorLodha, Rakesh
dc.contributor.authorLogroscino, Giancarlo
dc.contributor.authorLondon, Stephanie J
dc.contributor.authorLooker, Katharine J
dc.contributor.authorLopez, Alan D
dc.contributor.authorLorkowski, Stefan
dc.contributor.authorLotufo, Paulo A
dc.contributor.authorLow, Nicola
dc.contributor.authorLozano, Rafael
dc.contributor.authorLucas, Timothy CD
dc.contributor.authorMacarayan, Erlyn Rachelle King
dc.contributor.authorAbd El Razek, Hassan Magdy
dc.contributor.authorAbd El Razek, Mohammed Magdy
dc.contributor.authorMahdavi, Mahdi
dc.contributor.authorMajdan, Marek
dc.contributor.authorMajdzadeh, Reza
dc.contributor.authorMajeed, Azeem
dc.contributor.authorMalekzadeh, Reza
dc.contributor.authorMalhotra, Rajesh
dc.contributor.authorMalta, Deborah Carvalho
dc.contributor.authorMamun, Abdullah A
dc.contributor.authorManguerra, Helena
dc.contributor.authorManhertz, Treh
dc.contributor.authorMantilla, Ana
dc.contributor.authorMantovani, Lorenzo G
dc.contributor.authorMapoma, Chabila C
dc.contributor.authorMarczak, Laurie B
dc.contributor.authorMartinez-Raga, Jose
dc.contributor.authorMartins-Melo, Francisco Rogerlandio
dc.contributor.authorMartopullo, Ira
dc.contributor.authorMaerz, Winfried
dc.contributor.authorMathur, Manu Raj
dc.contributor.authorMazidi, Mohsen
dc.contributor.authorMcAlinden, Colm
dc.contributor.authorMcGaughey, Madeline
dc.contributor.authorMcGrath, John J
dc.contributor.authorMckee, Martin
dc.contributor.authorMcNellan, Claire
dc.contributor.authorMehata, Suresh
dc.contributor.authorMehndiratta, Man Mohan
dc.contributor.authorMekonnen, Tefera Chane
dc.contributor.authorMemiah, Peter
dc.contributor.authorMemish, Ziad A
dc.contributor.authorMendoza, Walter
dc.contributor.authorMengistie, Mubarek Abera
dc.contributor.authorMengistu, Desalegn Tadese
dc.contributor.authorMensah, George A
dc.contributor.authorMeretoja, Atte
dc.contributor.authorMeretoja, Tuomo J
dc.contributor.authorMezgebe, Haftay Berhane
dc.contributor.authorMicha, Renata
dc.contributor.authorMillear, Anoushka
dc.contributor.authorMiller, Ted R
dc.contributor.authorMills, Edward J
dc.contributor.authorMirarefin, Mojde
dc.contributor.authorMirrakhimov, Erkin M
dc.contributor.authorMisganaw, Awoke
dc.contributor.authorMishra, Shiva Raj
dc.contributor.authorMitchell, Philip B
dc.contributor.authorMohammad, Karzan Abdulmuhsin
dc.contributor.authorMohammadi, Alireza
dc.contributor.authorMohammed, Kedir Endris
dc.contributor.authorMohammed, Shafiu
dc.contributor.authorMohanty, Sanjay K
dc.contributor.authorMokdad, Ali H
dc.contributor.authorMollenkopf, Sarah K
dc.contributor.authorMonasta, Lorenzo
dc.contributor.authorMontanez Hernandez, Julio
dc.contributor.authorMontico, Marcella
dc.contributor.authorMoradi-Lakeh, Maziar
dc.contributor.authorMoraga, Paula
dc.contributor.authorMori, Rintaro
dc.contributor.authorMorozoff, Chloe
dc.contributor.authorMorrison, Shane D
dc.contributor.authorMoses, Mark
dc.contributor.authorMountjoy-Venning, Cliff
dc.contributor.authorMruts, Kalayu Birhane
dc.contributor.authorMueller, Ulrich O
dc.contributor.authorMuller, Kate
dc.contributor.authorMurdoch, Michele E
dc.contributor.authorMurthy, Gudlavalleti Venkata Satyanarayana
dc.contributor.authorMusa, Kamarul Imran
dc.contributor.authorNachega, Jean B
dc.contributor.authorNagel, Gabriele
dc.contributor.authorNaghavi, Mohsen
dc.contributor.authorNaheed, Aliya
dc.contributor.authorNaidoo, Kovin S
dc.contributor.authorNaldi, Luigi
dc.contributor.authorNangia, Vinay
dc.contributor.authorNatarajan, Gopalakrishnan
dc.contributor.authorNegasa, Dumessa Edessa
dc.contributor.authorNegoi, Ionut
dc.contributor.authorNegoi, Ruxandra Irina
dc.contributor.authorNewton, Charles R
dc.contributor.authorNgunjiri, Josephine Wanjiku
dc.contributor.authorCuong, Tat Nguyen
dc.contributor.authorNguyen, Grant
dc.contributor.authorNguyen, Minh
dc.contributor.authorQuyen, Le Nguyen
dc.contributor.authorTrang, Huyen Nguyen
dc.contributor.authorNichols, Emma
dc.contributor.authorNingrum, Dina Nur Anggraini
dc.contributor.authorNolte, Sandra
dc.contributor.authorVuong, Minh Nong
dc.contributor.authorNorrving, Bo
dc.contributor.authorNoubiap, Jean Jacques N
dc.contributor.authorO'Donnell, Martin J
dc.contributor.authorOgbo, Felix Akpojene
dc.contributor.authorOh, In-Hwan
dc.contributor.authorOkoro, Anselm
dc.contributor.authorOladimeji, Olanrewaju
dc.contributor.authorOlagunju, Andrew Toyin
dc.contributor.authorOlagunju, Tinuke Oluwasefunmi
dc.contributor.authorOlsen, Helen E
dc.contributor.authorOlusanya, Bolajoko Olubukunola
dc.contributor.authorOlusanya, Jacob Olusegun
dc.contributor.authorOng, Kanyin
dc.contributor.authorOpio, John Nelson
dc.contributor.authorOren, Eyal
dc.contributor.authorOrtiz, Alberto
dc.contributor.authorOsgood-Zimmerman, Aaron
dc.contributor.authorOsman, Majdi
dc.contributor.authorOwolabi, Mayowa O
dc.contributor.authorMahesh, PA
dc.contributor.authorPacella, Rosana E
dc.contributor.authorPana, Adrian
dc.contributor.authorPanda, Basant Kumar
dc.contributor.authorPapachristou, Christina
dc.contributor.authorPark, Eun-Kee
dc.contributor.authorParry, Charles D
dc.contributor.authorParsaeian, Mahboubeh
dc.contributor.authorPatten, Scott B
dc.contributor.authorPatton, George C
dc.contributor.authorPaulson, Katherine
dc.contributor.authorPearce, Neil
dc.contributor.authorPereira, David M
dc.contributor.authorPerico, Norberto
dc.contributor.authorPesudovs, Konrad
dc.contributor.authorPeterson, Carrie Beth
dc.contributor.authorPetzold, Max
dc.contributor.authorPhillips, Michael Robert
dc.contributor.authorPigott, David M
dc.contributor.authorPillay, Julian David
dc.contributor.authorPinho, Christine
dc.contributor.authorPlass, Dietrich
dc.contributor.authorPletcher, Martin A
dc.contributor.authorPopova, Svetlana
dc.contributor.authorPoulton, Richie G
dc.contributor.authorPourmalek, Farshad
dc.contributor.authorPrabhakaran, Dorairaj
dc.contributor.authorPrasad, Narayan
dc.contributor.authorPrasad, Noela M
dc.contributor.authorPurcell, Carrie
dc.contributor.authorQorbani, Mostafa
dc.contributor.authorQuansah, Reginald
dc.contributor.authorRabiee, Rynaz HS
dc.contributor.authorRadfar, Amir
dc.contributor.authorRafay, Anwar
dc.contributor.authorRahimi, Kazem
dc.contributor.authorRahimi-Movaghar, Afarin
dc.contributor.authorRahimi-Movaghar, Vafa
dc.contributor.authorRahman, Mahfuzar
dc.contributor.authorRahman, Mohammad Hifz Ur
dc.contributor.authorRai, Rajesh Kumar
dc.contributor.authorRajsic, Sasa
dc.contributor.authorRam, Usha
dc.contributor.authorRanabhat, Chhabi Lal
dc.contributor.authorRankin, Zane
dc.contributor.authorRao, Paturi Vishnupriya
dc.contributor.authorRao, Puja C
dc.contributor.authorRawaf, Salman
dc.contributor.authorRay, Sarah E
dc.contributor.authorReiner, Robert C
dc.contributor.authorReinig, Nikolas
dc.contributor.authorReitsma, Marissa B
dc.contributor.authorRemuzzi, Giuseppe
dc.contributor.authorRenzaho, Andre MN
dc.contributor.authorResnikoff, Serge
dc.contributor.authorRezaei, Satar
dc.contributor.authorRibeiro, Antonio L
dc.contributor.authorRonfani, Luca
dc.contributor.authorRoshandel, Gholamreza
dc.contributor.authorRoth, Gregory A
dc.contributor.authorRoy, Ambuj
dc.contributor.authorRubagotti, Enrico
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dc.date.accessioned2018-03-21T05:22:38Z
dc.date.available2018-03-21T05:22:38Z
dc.date.issued2017
dc.identifier.issn0140-6736
dc.identifier.doi10.1016/S0140-6736(17)32154-2
dc.identifier.urihttp://hdl.handle.net/10072/371970
dc.description.abstractBackground As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016. Methods We estimated prevalence and incidence for 328 diseases and injuries and 2982 sequelae, their non-fatal consequences. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between incidence, prevalence, remission, and cause of death rates for each condition. For some causes, we used alternative modelling strategies if incidence or prevalence needed to be derived from other data. YLDs were estimated as the product of prevalence and a disability weight for all mutually exclusive sequelae, corrected for comorbidity and aggregated to cause level. We updated the Socio-demographic Index (SDI), a summary indicator of income per capita, years of schooling, and total fertility rate. GBD 2016 complies with the Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER). Findings Globally, low back pain, migraine, age-related and other hearing loss, iron-deficiency anaemia, and major depressive disorder were the five leading causes of YLDs in 2016, contributing 57·6 million (95% uncertainty interval [UI] 40·8–75·9 million [7·2%, 6·0–8·3]), 45·1 million (29·0–62·8 million [5·6%, 4·0–7·2]), 36·3 million (25·3–50·9 million [4·5%, 3·8–5·3]), 34·7 million (23·0–49·6 million [4·3%, 3·5–5·2]), and 34·1 million (23·5–46·0 million [4·2%, 3·2–5·3]) of total YLDs, respectively. Age-standardised rates of YLDs for all causes combined decreased between 1990 and 2016 by 2·7% (95% UI 2·3–3·1). Despite mostly stagnant age-standardised rates, the absolute number of YLDs from non-communicable diseases has been growing rapidly across all SDI quintiles, partly because of population growth, but also the ageing of populations. The largest absolute increases in total numbers of YLDs globally were between the ages of 40 and 69 years. Age-standardised YLD rates for all conditions combined were 10·4% (95% UI 9·0–11·8) higher in women than in men. Iron-deficiency anaemia, migraine, Alzheimer’s disease and other dementias, major depressive disorder, anxiety, and all musculoskeletal disorders apart from gout were the main conditions contributing to higher YLD rates in women. Men had higher age-standardised rates of substance use disorders, diabetes, cardiovascular diseases, cancers, and all injuries apart from sexual violence. Globally, we noted much less geographical variation in disability than has been documented for premature mortality. In 2016, there was a less than two times difference in age-standardised YLD rates for all causes between the location with the lowest rate (China, 9201 YLDs per 100000, 95% UI 6862–11943) and highest rate (Yemen, 14774 YLDs per 100000, 11018–19228). Interpretation The decrease in death rates since 1990 for most causes has not been matched by a similar decline in age-standardised YLD rates. For many large causes, YLD rates have either been stagnant or have increased for some causes, such as diabetes. As populations are ageing, and the prevalence of disabling disease generally increases steeply with age, health systems will face increasing demand for services that are generally costlier than the interventions that have led to declines in mortality in childhood or for the major causes of mortality in adults. Up-todate information about the trends of disease and how this varies between countries is essential to plan for an adequate health-system response. Funding Bill & Melinda Gates Foundation, and the National Institute on Aging and the National Institute of Mental Health of the National Institutes of Health.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherThe Lancet Publishing Group
dc.relation.ispartofpagefrom1211
dc.relation.ispartofpageto1259
dc.relation.ispartofissue10100
dc.relation.ispartofjournalThe Lancet
dc.relation.ispartofvolume390
dc.subject.fieldofresearchMedical and Health Sciences not elsewhere classified
dc.subject.fieldofresearchMedical and Health Sciences
dc.subject.fieldofresearchcode119999
dc.subject.fieldofresearchcode11
dc.titleGlobal, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttps://creativecommons.org/licenses/by/4.0/
dc.description.versionPublished
gro.rights.copyright© The Author(s). Published by Elsevier Ltd. This is an Open Access article under the terms of the Creative Commons Attribution 4.0 International (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorDe Leo, Diego
gro.griffith.authorLalloo, Ratilal
gro.griffith.authorMcGrath, John J.


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