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dc.contributor.authorTong, X
dc.contributor.authorPoon, J
dc.contributor.authorLi, A
dc.contributor.authorKit, C
dc.contributor.authorYamada, A
dc.contributor.authorShiino, K
dc.contributor.authorLing, LF
dc.contributor.authorChoe, YH
dc.contributor.authorChan, J
dc.contributor.authorLau, Y-K
dc.contributor.authorNg, M-Y
dc.date.accessioned2019-05-29T12:32:42Z
dc.date.available2019-05-29T12:32:42Z
dc.date.issued2018
dc.identifier.issn0009-9260
dc.identifier.doi10.1016/j.crad.2017.10.019
dc.identifier.urihttp://hdl.handle.net/10072/373139
dc.description.abstractAIM: To investigate the accuracy of cardiac magnetic resonance (CMR) tissue tracking (CMRTT) and speckle tracking echocardiography (STE) against CMR determined right ventricular (RV) ejection fraction (RVEF) and to identify an optimal cut-off value for STE and CMR-TT to determine RVEF <45% and compare this to other conventional methods for estimating RVEF in dilated cardiomyopathy (DCM) patients. MATERIALS AND METHODS: Twenty-nine DCM patients were recruited prospectively. CMR and echocardiography were performed within 48 hours and four-chamber views were used for strain analysis. Contoured CMR short axis images provided RVEF. Intraclass correlation coefficient (ICC), bias, levels of agreement, and receiver operating characteristic (ROC) curve analyses were performed. RESULTS: CMR-TT RV free-wall longitudinal strain (FLS) and STE RV global longitudinal strain (GLS) showed the best correlation with RVEF (r¼e0.68, r¼e0.82, p<0.001 respectively). There was moderate correlation between echocardiography RV GLS and CMR RV FLS (r¼0.64, p<0.001). CMR-TT FLS showed excellent intra-observer and interobserver reliability (ICC¼0.980; ICC¼0.968 respectively). STE GLS correlated better with RVEF than with peak systolic annular velocity (S’; r¼0.45), tricuspid annular plane systolic excursion (TAPSE; r¼0.56), and fractional area change (FAC; r¼0.78). CMR-TT RV FLS had better correlation with RVEF than CMR TAPSE (r¼0.69 versus 0.40). ROC analysis demonstrated the optimal cut-off value for CMR-TT RV FLS and STE GLS in detection of RVEF <45% was e24.4% (area under the curve¼0.87, 100% sensitivity, 66.7% specificity) and e20.9% (area under the curve¼0.88, 100% sensitivity, 60% specificity) respectively. CONCLUSION: CMR-TT FLS and STE GLS showed potential to provide rapid assessment of RV function and had superior correlation with RVEF compared to conventional parameters.
dc.description.peerreviewedYes
dc.languageEnglish
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.relation.ispartofchapter324
dc.relation.ispartofpagefrome9
dc.relation.ispartofpagetoe18
dc.relation.ispartofissue3
dc.relation.ispartofjournalClinical Radiology
dc.relation.ispartofvolume73
dc.subject.fieldofresearchClinical Sciences not elsewhere classified
dc.subject.fieldofresearchClinical Sciences
dc.subject.fieldofresearchcode110399
dc.subject.fieldofresearchcode1103
dc.titleValidation of cardiac magnetic resonance tissue tracking in the rapid assessment of RV function: A comparative study to echocardiography
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorLau, Kam
gro.griffith.authorYamada, Akira
gro.griffith.authorChan, Jonathan H.
gro.griffith.authorShiino, Kenji


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