Show simple item record

dc.contributor.authorRehm, Fabian B.H.
dc.contributor.authorGrage, Katrin
dc.contributor.authorRehm, Bernd H.A.
dc.contributor.editorSang Yup Lee
dc.date.accessioned2018-10-23T12:31:47Z
dc.date.available2018-10-23T12:31:47Z
dc.date.issued2017
dc.identifier.isbn9783319504353
dc.identifier.doi10.1007/978-3-319-50436-0_377
dc.identifier.urihttp://hdl.handle.net/10072/373406
dc.description.abstractMicroorganisms produce a variety of different polymers such as polyamides, polysaccharides, and polyesters. The polyesters, the polyhydroxyalkanoates (PHAs), are the most extensively studied polymers in regard to their use in display technology. The material properties of bacterial PHAs in combination with their biocompatibility and biodegradability make them attractive substrates for use in display technology applications. By translationally fusing bioactive molecules to a gene encoding a PHA-binding domain, the appropriate functionalization for a given application can be achieved such that the need for chemical immobilization is circumvented. By separately extracting and processing the biopolymer, using it to coat a surface, and then treating this surface with the fusion proteins, surface functionalization for immunodiagnostic microarray or tissue engineering applications can be accomplished. Conversely, by expressing the fusion protein directly in the PHA-producing organisms, one-step production of functionalized beads can be achieved. Such beads have been demonstrated in diverse applications, including fluorescence-activated cell sorting, enzyme-linked immunosorbent assays, microarrays, diagnostic skin test for tuberculosis, vaccines, protein purification, and affinity bioseparation.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherSpringer International Publishing AG
dc.publisher.placeSwitzerland
dc.relation.ispartofbooktitleConsequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals
dc.relation.ispartofchapter31
dc.relation.ispartofpagefrom569
dc.relation.ispartofpageto586
dc.relation.ispartofedition1st
dc.relation.ispartofvolume1
dc.subject.fieldofresearchMicrobiology not elsewhere classified
dc.subject.fieldofresearchcode060599
dc.titleApplications of Microbial Biopolymers in Display Technology
dc.typeBook chapter
dc.type.descriptionB1 - Chapters
dc.type.codeB - Book Chapters
gro.hasfulltextNo Full Text
gro.griffith.authorRehm, Bernd


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Book chapters
    Contains book chapters authored by Griffith authors.

Show simple item record