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  • The SIESTA trial: A randomized study investigating the efficacy, safety, and tolerability of acupressure versus sham therapy for improving sleep quality in patients with end-stage kidney disease on hemodialysis

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    Author(s)
    Shen, Kunyu
    Cho, Yeoungjee
    Pascoe, Elaine M
    Hawley, Carmel M
    Oliver, Veronica
    Hughes, Kathryn M
    Baer, Richard
    Frazier, Jeremy
    Jarvis, Elizabeth
    Tan, Ken-Soon
    Liu, Xusheng
    Gobe, Glenda
    Johnson, David W
    Griffith University Author(s)
    Tan, Ken-Soon
    Frazier, Jeremy
    Baer, Richard
    Year published
    2017
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    Abstract
    Objectives. To compare the effectiveness of real acupressure versus sham acupressure therapy in improving sleep quality in patients receiving hemodialysis (HD) or hemodiafiltration (HDF). Methods. A multicenter, single-blind, randomized controlled trial was conducted in two Australian dialysis units located in Princess Alexandra Hospital and Logan Hospital, respectively. Forty-two subjects with self-reported poor sleep quality were randomly assigned to real (𝑛 = 21) or sham (𝑛 = 21) acupressure therapy delivered thrice weekly for four consecutive weeks during routine dialysis sessions. The primary outcome was the Pittsburgh ...
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    Objectives. To compare the effectiveness of real acupressure versus sham acupressure therapy in improving sleep quality in patients receiving hemodialysis (HD) or hemodiafiltration (HDF). Methods. A multicenter, single-blind, randomized controlled trial was conducted in two Australian dialysis units located in Princess Alexandra Hospital and Logan Hospital, respectively. Forty-two subjects with self-reported poor sleep quality were randomly assigned to real (𝑛 = 21) or sham (𝑛 = 21) acupressure therapy delivered thrice weekly for four consecutive weeks during routine dialysis sessions. The primary outcome was the Pittsburgh Sleep Quality Index (PSQI) score measured at week four adjusted for baseline PSQI measurements. Secondary outcomes were quality of life (QOL) (SF-8), adverse events, and patient acceptability (treatment acceptability questionnaire, TAQ). Results. The two groups were comparable on global PSQI scores (difference 0.19, 95% confidence interval [CI] −1.32 to 1.70) and on the subscale scores. Similar results were observed for QOL both in the mental (difference −3.88, 95% CI −8.63 to 0.87) and the physical scores (difference 2.45, 95% CI −1.69 to 6.58). There were no treatment-related adverse events and acupressure was perceived favorably by participants. Conclusion. Acupressure is a safe, well-tolerated, and highly acceptable therapy in adult hemodialysis patients in a Western healthcare setting with uncertain implications for therapeutic efficacy.
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    Journal Title
    Evidence-based Complementary and Alternative Medicine
    Volume
    2017
    DOI
    https://doi.org/10.1155/2017/7570352
    Copyright Statement
    © 2017 Kunyu Shen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
    Subject
    Complementary and Alternative Medicine not elsewhere classified
    Complementary and Alternative Medicine
    Publication URI
    http://hdl.handle.net/10072/374340
    Collection
    • Journal articles

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