Show simple item record

dc.contributor.authorChavas, Leonard MG
dc.contributor.authorKato, Ryuichi
dc.contributor.authorSuzuki, Nobuhiro
dc.contributor.authorvon Itzstein, Mark
dc.contributor.authorMann, Maretta C
dc.contributor.authorThomson, Robin J
dc.contributor.authorDyason, Jeffrey C
dc.contributor.authorMcKimm-Breschkin, Jennifer
dc.contributor.authorFusi, Paola
dc.contributor.authorTringali, Cristina
dc.contributor.authorVenerando, Bruno
dc.contributor.authorTettamanti, Guido
dc.contributor.authorMonti, Eugenio
dc.contributor.authorWakatsuki, Soichi
dc.date.accessioned2017-05-03T12:40:12Z
dc.date.available2017-05-03T12:40:12Z
dc.date.issued2010
dc.date.modified2011-03-23T05:44:50Z
dc.identifier.issn0022-2623
dc.identifier.doi10.1021/jm100078r
dc.identifier.urihttp://hdl.handle.net/10072/37591
dc.description.abstractWith the global spread of the pandemic H1N1 and the ongoing pandemic potential of the H5N1 subtype, the influenza virus represents one of the most alarming viruses spreading worldwide. The influenza virus sialidase is an effective drug target, and a number of inhibitors are clinically effective against the virus (zanamivir, oseltamivir, peramivir). Here we report structural and biochemical studies of the human cytosolic sialidase Neu2 with influenza virus sialidase-targeting drugs and related compounds.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoen_AU
dc.publisherAmerican Chemical Society
dc.publisher.placeUnited States
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom2998
dc.relation.ispartofpageto3002
dc.relation.ispartofissue7
dc.relation.ispartofjournalJournal of Medicinal Chemistry
dc.relation.ispartofvolume53
dc.rights.retentionY
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry not elsewhere classified
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry
dc.subject.fieldofresearchPharmacology and Pharmaceutical Sciences
dc.subject.fieldofresearchOrganic Chemistry
dc.subject.fieldofresearchcode030499
dc.subject.fieldofresearchcode0304
dc.subject.fieldofresearchcode1115
dc.subject.fieldofresearchcode0305
dc.titleComplexity in Influenza Virus Targeted Drug Design: Interaction with Human Sialidases
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.rights.copyrightSelf-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the author[s] for more information.
gro.date.issued2010
gro.hasfulltextNo Full Text
gro.griffith.authorvon Itzstein, Mark
gro.griffith.authorThomson, Robin J.
gro.griffith.authorDyason, Jeffrey C.
gro.griffith.authorMann, Maretta C.


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record