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dc.contributor.authorM. G. Chavas, Leonarden_US
dc.contributor.authorKato, Ryuichien_US
dc.contributor.authorSuzuki, Nobuhiroen_US
dc.contributor.authorvon Itzstein, Marken_US
dc.contributor.authorMann, Marettaen_US
dc.contributor.authorThomson, Robinen_US
dc.contributor.authorDyason, Jeffreyen_US
dc.contributor.authorMcKimm-Breschkin, Jenniferen_US
dc.contributor.authorFusi, Paolaen_US
dc.contributor.authorTringali, Cristinaen_US
dc.contributor.authorVenerando, Brunoen_US
dc.contributor.authorTettamanti, Guidoen_US
dc.contributor.authorMonti, Eugenioen_US
dc.contributor.authorWakatsuki, Soichien_US
dc.date.accessioned2017-04-24T09:42:11Z
dc.date.available2017-04-24T09:42:11Z
dc.date.issued2010en_US
dc.date.modified2011-03-23T05:44:50Z
dc.identifier.issn00222623en_US
dc.identifier.doi10.1021/jm100078ren_AU
dc.identifier.urihttp://hdl.handle.net/10072/37591
dc.description.abstractWith the global spread of the pandemic H1N1 and the ongoing pandemic potential of the H5N1 subtype, the influenza virus represents one of the most alarming viruses spreading worldwide. The influenza virus sialidase is an effective drug target, and a number of inhibitors are clinically effective against the virus (zanamivir, oseltamivir, peramivir). Here we report structural and biochemical studies of the human cytosolic sialidase Neu2 with influenza virus sialidase-targeting drugs and related compounds.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherAmerican Chemical Societyen_US
dc.publisher.placeUnited Statesen_US
dc.relation.ispartofstudentpublicationNen_AU
dc.relation.ispartofpagefrom2998en_US
dc.relation.ispartofpageto3002en_US
dc.relation.ispartofissue7en_US
dc.relation.ispartofjournalJournal of Medicinal Chemistryen_US
dc.relation.ispartofvolume53en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchMedicinal and Biomolecular Chemistry not elsewhere classifieden_US
dc.subject.fieldofresearchcode030499en_US
dc.titleComplexity in Influenza Virus Targeted Drug Design: Interaction with Human Sialidasesen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.rights.copyrightSelf-archiving of the author-manuscript version is not yet supported by this journal. Please refer to the journal link for access to the definitive, published version or contact the author[s] for more information.en_AU
gro.date.issued2010
gro.hasfulltextNo Full Text


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