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dc.contributor.authorM. Reiman, Jenniferen_US
dc.contributor.authorKnutson, Keithen_US
dc.contributor.authorRadisky, Dereken_US
dc.date.accessioned2017-04-24T13:33:38Z
dc.date.available2017-04-24T13:33:38Z
dc.date.issued2010en_US
dc.date.modified2011-03-23T05:48:02Z
dc.identifier.issn15387445en_US
dc.identifier.doi10.1158/0008-5472.CAN-09-4041en_AU
dc.identifier.urihttp://hdl.handle.net/10072/37678
dc.description.abstractElements of the immune system act as intimate regulators of cancer progression, inhibiting early stages of tumor growth, through immunosurveillance while facilitating later stages of tumor progression. Recent findings have revealed that activated CD8 T cells can stimulate mammary epithelial tumor cells to undergo epithelial-mesenchymal transition (EMT) and to acquire the greatly increased tumorigenic capability and chemotherapeutic resistance of breast cancer stem cells (BCSC). These studies provide a window to understanding how BCSC arise and are maintained within tumors, and how to best target these processes for therapeutic benefit.en_US
dc.description.peerreviewedYesen_US
dc.description.publicationstatusYesen_AU
dc.languageEnglishen_US
dc.language.isoen_AU
dc.publisherAmerican Association for Cancer Researchen_US
dc.publisher.placeUnited Statesen_US
dc.relation.ispartofstudentpublicationYen_AU
dc.relation.ispartofpagefrom3005en_US
dc.relation.ispartofpageto3008en_US
dc.relation.ispartofissue8en_US
dc.relation.ispartofjournalCancer Researchen_US
dc.relation.ispartofvolume70en_US
dc.rights.retentionYen_AU
dc.subject.fieldofresearchTumour Immunologyen_US
dc.subject.fieldofresearchcode110709en_US
dc.titleImmune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cellsen_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Peer Reviewed (HERDC)en_US
dc.type.codeC - Journal Articlesen_US
gro.date.issued2010
gro.hasfulltextNo Full Text


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