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dc.contributor.authorMcMillan, DJ
dc.contributor.authorVu, T
dc.contributor.authorBramhachari, PV
dc.contributor.authorKaul, SY
dc.contributor.authorBouvet, A
dc.contributor.authorShaila, MS
dc.contributor.authorKarmarkar, MG
dc.contributor.authorSriprakash, KS
dc.date.accessioned2017-05-03T14:52:29Z
dc.date.available2017-05-03T14:52:29Z
dc.date.issued2010
dc.date.modified2011-04-08T04:46:02Z
dc.identifier.issn0934-9723
dc.identifier.doi10.1007/s10096-010-0899-x
dc.identifier.urihttp://hdl.handle.net/10072/38032
dc.description.abstractGiven the increasing aetiological importance of Streptococcus dysgalactiae subspecies equisimilis in diseases which are primarily attributed to S. pyogenes, molecular markers are essential to distinguish these species and delineate their epidemiology more precisely. Many clinical microbiology laboratories rely on agglutination reactivity and biochemical tests to distinguish them. These methods have limitations which are particularly exacerbated when isolates with mixed properties are encountered. In order to provide additional distinguishing parameters that could be used to unequivocally discriminate these two common pathogens, we assess here three molecular targets: the speB gene, intergenic region upstream of the scpG gene (IRSG) and virPCR. Of these, the former two respectively gave positive and negative results for S. pyogenes, and negative and positive results for S. dysgalactiae subsp. equisimilis. Thus, a concerted use of these nucleic acid-based methods is particularly helpful in epidemiological surveillance to accurately assess the relative contribution of these species to streptococcal infections and diseases.
dc.description.peerreviewedYes
dc.description.publicationstatusYes
dc.languageEnglish
dc.language.isoen_AU
dc.publisherSpringer
dc.publisher.placeGermany
dc.relation.ispartofstudentpublicationN
dc.relation.ispartofpagefrom585
dc.relation.ispartofpageto589
dc.relation.ispartofissue5
dc.relation.ispartofjournalEuropean Journal of Clinical Microbiology & Infectious Diseases
dc.relation.ispartofvolume29
dc.rights.retentionY
dc.subject.fieldofresearchMicrobiology not elsewhere classified
dc.subject.fieldofresearchBiological Sciences
dc.subject.fieldofresearchMedical and Health Sciences
dc.subject.fieldofresearchcode060599
dc.subject.fieldofresearchcode06
dc.subject.fieldofresearchcode11
dc.titleMolecular markers for discriminating Streptococcus pyogenes and S. dysgalactiae subspecies equisimilis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.facultyGriffith Health, Griffith University Medical Research College
gro.date.issued2010
gro.hasfulltextNo Full Text
gro.griffith.authorMcMillan, Dave
gro.griffith.authorMcMillan, David J.
gro.griffith.authorSriprakash, Kadaba S.


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