Show simple item record

dc.contributor.authorCanellas, JVDS
dc.contributor.authorMedeiros, PJD
dc.contributor.authorFigueredo, CMDS
dc.contributor.authorFischer, RG
dc.contributor.authorRitto, FG
dc.date.accessioned2019-07-04T12:31:32Z
dc.date.available2019-07-04T12:31:32Z
dc.date.issued2019
dc.identifier.issn0901-5027
dc.identifier.doi10.1016/j.ijom.2018.07.007
dc.identifier.urihttp://hdl.handle.net/10072/380572
dc.description.abstractThe effect of platelet-rich fibrin (PRF) in enhancing the healing after oral surgical interventions is still a matter of debate. The purpose of this study was to identify instances where PRF has been shown to be effective in oral surgical procedures. A comprehensive literature search was performed up to 2017 on PubMed/MEDLINE, Cochrane Library, Web of Science, Scopus and LILACS databases and grey literature. The full-text of potentially relevant studies were reviewed and only randomized clinical trials (RCTs) were included. A total of 559 studies were found, of which 30 were included for qualitative analysis and 13 for quantitative analysis. Three review authors assessed the risk of bias independently. The available literature suggests that PRF has a positive effect in improving alveolar preservation on extraction sockets and around dental implants. The qualitative analysis showed a significantly better effect of PRF in promoting bone regeneration for alveolar cleft reconstruction. The meta-analysis for third molar surgery showed a decrease in prevalence of alveolar osteitis. PRF increased implant stability 1 week and 1 month after surgery (P = 0.0005 and 0.0003). Due to the lack of studies with low risk of bias and a limited number of patients available, further RCTs are needed to confirm these results.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto20
dc.relation.ispartofjournalInternational Journal of Oral and Maxillofacial Surgery
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchPeriodontics
dc.subject.fieldofresearchcode3203
dc.subject.fieldofresearchcode320310
dc.titlePlatelet-rich fibrin in oral surgical procedures: a systematic review and meta-analysis
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.description.versionAccepted Manuscript (AM)
gro.description.notepublicThis publication has been entered into Griffith Research Online as an Advanced Online Version.
gro.rights.copyright© 2018 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorda Silva Figueredo, Carlos Marcelo


Files in this item

This item appears in the following Collection(s)

  • Journal articles
    Contains articles published by Griffith authors in scholarly journals.

Show simple item record