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  • Association between developmental defects of enamel and dental caries: a systematic review and meta-analysis

    Author(s)
    Vargas-Ferreira, F
    Salas, M
    Nascimento-Carvalho, Cristiana
    Nascimento, Gustavo
    Tarquinio, Sandra
    Faggion Jr., Clovis
    Peres, Marco
    Thomson, W
    Demarco, Fl
    Griffith University Author(s)
    Peres, Marco A.
    Year published
    2018
    Metadata
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    Abstract
    Background: Dental caries is the main problem oral health and it is not well established in the literature if the enamel defects are a risk factor for its development. Objective: Studies have reported a potential association between developmental defects enamel (DDE) and dental caries occurrence. We investigated the association between DDE and caries in permanent dentition of children and teenagers. Data sources: A systematic review was carried out using four databases (Pubmed, Web of Science, Embase, andScienceDirect), which were searchedfromtheir earliest recordsuntilDecember 31, 2014. Study selection: Population-based ...
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    Background: Dental caries is the main problem oral health and it is not well established in the literature if the enamel defects are a risk factor for its development. Objective: Studies have reported a potential association between developmental defects enamel (DDE) and dental caries occurrence. We investigated the association between DDE and caries in permanent dentition of children and teenagers. Data sources: A systematic review was carried out using four databases (Pubmed, Web of Science, Embase, andScienceDirect), which were searchedfromtheir earliest recordsuntilDecember 31, 2014. Study selection: Population-based studies assessing differences in dental caries experience according to the presence of enamel defects (and their types) were included. PRISMA guidelines for reporting systematic reviews were followed. Meta-analysis was performed to assess the pooled effect, and meta-regression was carried out to identify heterogeneity sources. From the 2558 initially identified papers, nine studies fulfilled all inclusion criteria after checking the titles, abstracts, references, and complete reading. Seven of them were included in the meta-analysis with random model. Results: A positive association between enamel defects and dental caries was identified; metaanalysis showed that individuals with DDE had higher pooled odds of having dental caries experience [OR 2.21 (95% CI 1.3; 3.54)]. Meta-regression analysis demonstrated that adjustment for sociodemographic factors, countries’ socioeconomic status, and bias (quality of studies) explained the high heterogeneity observed. Conclusion: A higher chance of dental caries should be expected among individuals with enamel defects.
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    Journal Title
    Journal of Dentistry
    Volume
    43
    Issue
    6
    DOI
    https://doi.org/10.1016/j.jdent.2015.03.011
    Subject
    Dentistry
    Dentistry not elsewhere classified
    Publication URI
    http://hdl.handle.net/10072/380631
    Collection
    • Journal articles

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