dc.contributor.author | Atabila, Albert | |
dc.contributor.author | Sadler, Ross | |
dc.contributor.author | Dung, Tri Phung | |
dc.contributor.author | Hogarh, Jonathan N | |
dc.contributor.author | Carswell, Stewart | |
dc.contributor.author | Turner, Scott | |
dc.contributor.author | Patel, Renu | |
dc.contributor.author | Connell, Des | |
dc.contributor.author | Chu, Cordia | |
dc.date.accessioned | 2019-07-04T12:41:25Z | |
dc.date.available | 2019-07-04T12:41:25Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 0944-1344 | |
dc.identifier.doi | 10.1007/s11356-018-2259-9 | |
dc.identifier.uri | http://hdl.handle.net/10072/381729 | |
dc.description.abstract | Chlorpyrifos is a neurotoxic insecticide that is widely used in the agricultural sector of Ghana. The main objective of this study
was to evaluate the levels of chlorpyrifos exposure and health risk among applicators (n = 21) on irrigated rice farms in Ghana,
based on a typical application event. Pre- and post-application urine samples (24-h) were collected from the applicators and
analysed for 3,5,6-trichloro-2-pyridinol (TCP), using LC-MS/MS. The levels of chlorpyrifos-absorbed dose with the applicators
were estimated from the urinary TCP levels. Prior to application, the median absorbed dose of chlorpyrifos (background
exposure) with the applicators was 0.2 μg/kg/day (range 0.05 to 2 μg/kg/day). Following application, the median absorbed dose
of chlorpyrifos (application exposure) increased 30-fold to 6 μg/kg/day (range 0.7 to 74 μg/kg/day). The mean elimination halflife (t1/2) of chlorpyrifos was calculated to be 50 h. Hazard quotient (HQ) values (HQ > 1) obtained with the chronic (10 μg/kg/
day) and acute (100 μg/kg/day) guideline values of the WHO suggested no risk of chronic or acute health effects, respectively,
among both the median and 5% highly exposed groups. However, HQ values (HQ > 1) obtained with the chronic (0.3 μg/kg/day)
and acute (5 μg/kg/day) guideline values of the USEPA suggested risk of chronic and acute health effects, respectively, among
both the median and 5% highly exposed groups. The quantity of chlorpyrifos formulation applied, spraying duration, and the
number of spray tanks applied significantly correlated with the absorbed dose levels of chlorpyrifos from application exposure.
Therefore, these factors suggest means to reduce exposure and consequent health risk among the applicators. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | Springer | |
dc.publisher.place | Germany | |
dc.relation.ispartofpagefrom | 20854 | |
dc.relation.ispartofpageto | 20867 | |
dc.relation.ispartofissue | 21 | |
dc.relation.ispartofjournal | Environmental Science and Pollution Research | |
dc.relation.ispartofvolume | 25 | |
dc.subject.fieldofresearch | Chemical sciences | |
dc.subject.fieldofresearch | Environmental sciences | |
dc.subject.fieldofresearch | Other environmental sciences not elsewhere classified | |
dc.subject.fieldofresearch | Biological sciences | |
dc.subject.fieldofresearchcode | 34 | |
dc.subject.fieldofresearchcode | 41 | |
dc.subject.fieldofresearchcode | 419999 | |
dc.subject.fieldofresearchcode | 31 | |
dc.subject.keywords | Biomonitoring | |
dc.subject.keywords | Biomarker | |
dc.subject.keywords | Chlorpyrifos | |
dc.subject.keywords | Pesticide | |
dc.subject.keywords | Exposure assessment | |
dc.subject.keywords | Risk assessment | |
dc.title | Biomonitoring of chlorpyrifos exposure and health risk assessment among applicators on rice farms in Ghana | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
gro.faculty | Griffith Sciences, School of Environment and Science | |
gro.rights.copyright | © 2018 Springer-Verlag. This is an electronic version of an article published in Environmental Science and Pollution Research (ESPR), Vol. 25, pp. 20854–20867, 2018. Environmental Science and Pollution Research (ESPR) is available online at: http://link.springer.com// with the open URL of your article. | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Connell, Des W. | |
gro.griffith.author | Chu, Cordia M. | |
gro.griffith.author | Phung, Dung T. | |