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dc.contributor.authorHook, SE
dc.contributor.authorMondon, J
dc.contributor.authorRevill, AT
dc.contributor.authorGreenfield, PA
dc.contributor.authorSmith, RA
dc.contributor.authorTurner, RDR
dc.contributor.authorCorbett, PA
dc.contributor.authorWarne, MSJ
dc.date.accessioned2019-05-29T13:15:48Z
dc.date.available2019-05-29T13:15:48Z
dc.date.issued2018
dc.identifier.issn0141-1136
dc.identifier.doi10.1016/j.marenvres.2018.06.020
dc.identifier.urihttp://hdl.handle.net/10072/382009
dc.description.abstractBarramundi (Lates calcarifer) were collected at the beginning (1st sampling) and end (2nd sampling) of the wet season from Sandy Creek, an agriculturally impacted catchment in the Mackay Whitsundays region of the Great Barrier Reef catchment area, and from Repulse Creek, located approximately 100 km north in Conway National Park, to assess the impacts of pesticide exposure. Gill and liver histology, lipid class composition in muscle, and the hepatic transcriptome were examined. The first sample of Repulse Creek fish showed little tissue damage and low transcript levels of xenobiotic metabolism enzymes. Sandy Creek fish showed altered transcriptomic patterns, including those that regulate lipid metabolism, xenobiotic metabolism, and immune response; gross histological alterations including lipidosis; and differences in some lipid classes. The second sampling of Repulse Creek fish showed similar alterations in hepatic transcriptome and tissue structure as fish from Sandy Creek. These changes may indicate a decrease in health of pesticide exposed fish.
dc.description.peerreviewedYes
dc.languageeng
dc.publisherElsevier
dc.publisher.placeUnited Kingdom
dc.relation.ispartofpagefrom299
dc.relation.ispartofpageto321
dc.relation.ispartofjournalMarine Environmental Research
dc.relation.ispartofvolume140
dc.subject.fieldofresearchEnvironmental Sciences not elsewhere classified
dc.subject.fieldofresearchChemical Sciences
dc.subject.fieldofresearchEnvironmental Sciences
dc.subject.fieldofresearchBiological Sciences
dc.subject.fieldofresearchcode059999
dc.subject.fieldofresearchcode03
dc.subject.fieldofresearchcode05
dc.subject.fieldofresearchcode06
dc.titleTranscriptomic, lipid, and histological profiles suggest changes in health in fish from a pesticide hot spot
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.description.versionPost-print
gro.rights.copyright© 2018 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.
gro.hasfulltextFull Text
gro.griffith.authorWarne, Michael


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