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dc.contributor.authorHook, Sharonen_US
dc.contributor.authorMondon, Julieen_US
dc.contributor.authorRevill, Andrewen_US
dc.contributor.authorGreenfield, Paulen_US
dc.contributor.authorSmith, Rachaelen_US
dc.contributor.authorTurner, Ryanen_US
dc.contributor.authorCorbett, Patriciaen_US
dc.contributor.authorWarne, Michaelen_US
dc.date.accessioned2019-05-29T13:15:48Z
dc.date.available2019-05-29T13:15:48Z
dc.date.issued2018en_US
dc.identifier.issn0141-1136en_US
dc.identifier.doi10.1016/j.marenvres.2018.06.020en_US
dc.identifier.urihttp://hdl.handle.net/10072/382009
dc.description.abstractBarramundi (Lates calcarifer) were collected at the beginning (1st sampling) and end (2nd sampling) of the wet season from Sandy Creek, an agriculturally impacted catchment in the Mackay Whitsundays region of the Great Barrier Reef catchment area, and from Repulse Creek, located approximately 100 km north in Conway National Park, to assess the impacts of pesticide exposure. Gill and liver histology, lipid class composition in muscle, and the hepatic transcriptome were examined. The first sample of Repulse Creek fish showed little tissue damage and low transcript levels of xenobiotic metabolism enzymes. Sandy Creek fish showed altered transcriptomic patterns, including those that regulate lipid metabolism, xenobiotic metabolism, and immune response; gross histological alterations including lipidosis; and differences in some lipid classes. The second sampling of Repulse Creek fish showed similar alterations in hepatic transcriptome and tissue structure as fish from Sandy Creek. These changes may indicate a decrease in health of pesticide exposed fish.en_US
dc.description.peerreviewedYesen_US
dc.languageEnglishen_US
dc.publisherElsevieren_US
dc.publisher.placeUnited Kingdomen_US
dc.relation.ispartofpagefrom299en_US
dc.relation.ispartofpageto321en_US
dc.relation.ispartofjournalMarine Environmental Researchen_US
dc.relation.ispartofvolume140en_US
dc.subject.fieldofresearchEnvironmental Sciences not elsewhere classifieden_US
dc.subject.fieldofresearchChemical Sciencesen_US
dc.subject.fieldofresearchEnvironmental Sciencesen_US
dc.subject.fieldofresearchcode059999en_US
dc.subject.fieldofresearchcode03en_US
dc.subject.fieldofresearchcode05en_US
dc.titleTranscriptomic, lipid, and histological profiles suggest changes in health in fish from a pesticide hot spoten_US
dc.typeJournal articleen_US
dc.type.descriptionC1 - Articlesen_US
dc.type.codeC - Journal Articlesen_US
dcterms.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.description.versionPost-printen_US
gro.rights.copyright© 2018 Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence (http://creativecommons.org/licenses/by-nc-nd/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly cited.en_US
gro.hasfulltextFull Text
gro.griffith.authorWarne, Michael


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