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dc.contributor.authorAitken, Leanne M
dc.contributor.authorBucknall, Tracey
dc.contributor.authorKent, Bridie
dc.contributor.authorMitchell, Marion
dc.contributor.authorBurmeister, Elizabeth
dc.contributor.authorKeogh, Samantha J
dc.date.accessioned2019-06-19T13:02:31Z
dc.date.available2019-06-19T13:02:31Z
dc.date.issued2018
dc.identifier.issn1469-493X
dc.identifier.doi10.1002/14651858.CD009771.pub3
dc.identifier.urihttp://hdl.handle.net/10072/382099
dc.description.abstractBackground: The sedation needs of critically ill patients have been recognized as a core component of critical care that is vital to assist recovery and ensure humane treatment. Evidence suggests that sedation requirements are not always optimally managed. Suboptimal sedation, both under- and over-sedation, have been linked to short-term (e.g. length of stay) and long-term (e.g. psychological recovery) outcomes. Strategies to improve sedation assessment and management have been proposed. This review was originally published in 2015 and updated in 2018. Objectives: To assess the effects of protocol-directed sedation management compared to usual care on the duration of mechanical ventilation, intensive care unit (ICU) and hospital mortality and other patient outcomes in mechanically ventilated ICU adults and children. Search methods: We used the standard search strategy of the Cochrane Anaesthesia, Critical and Emergency Care Group (ACE). We searched the Cochrane Central Register of Controlled trials (CENTRAL) (December 2017), MEDLINE (OvidSP) (2013 to December 2017), Embase (OvidSP) (2013 to December 2017), CINAHL (BIREME host) (2013 to December 2017), LILACS (2013 to December 2017), trial registries and reference lists of articles. (The original search was run in November 2013).
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherJohn Wiley & Sons
dc.publisher.placeUnited Kingdom
dc.relation.ispartofpagefrom1
dc.relation.ispartofpageto52
dc.relation.ispartofjournalCochrane Database of Systematic Reviews
dc.relation.ispartofvolume11
dc.subject.fieldofresearchBiomedical and clinical sciences
dc.subject.fieldofresearchAcute care
dc.subject.fieldofresearchPsychology
dc.subject.fieldofresearchcode32
dc.subject.fieldofresearchcode420501
dc.subject.fieldofresearchcode52
dc.titleProtocol-directed sedation versus non-protocol-directed sedation in mechanically ventilated intensive care adults and children
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dc.description.versionVersion of Record (VoR)
gro.facultyGriffith Health, School of Nursing and Midwifery
gro.rights.copyright© 2018 The Cochrane Collaboration. Published by JohnWiley & Sons, Ltd. This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews YEAR, ISSUE. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.
gro.hasfulltextFull Text
gro.griffith.authorMitchell, Marion L.


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