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dc.contributor.authorAnderson, Nigel J
dc.contributor.authorJackson, James E
dc.contributor.authorSmith, Jennifer G
dc.contributor.authorWada, Morikatsu
dc.contributor.authorSchneider, Michal
dc.contributor.authorPoulsen, Michael
dc.contributor.authorRolfo, Maureen
dc.contributor.authorFahandej, Maziar
dc.contributor.authorGan, Hui
dc.contributor.authorJoon, Daryl Lim
dc.contributor.authorKhoo, Vincent
dc.date.accessioned2019-05-29T13:14:16Z
dc.date.available2019-05-29T13:14:16Z
dc.date.issued2018
dc.identifier.issn1043-3074
dc.identifier.doi10.1002/hed.25316
dc.identifier.urihttp://hdl.handle.net/10072/382180
dc.description.abstractBackground: The purpose of this study was to establish a risk stratification model for feeding tube use in patients who undergo intensity‐modulated radiotherapy (IMRT) for head and neck cancers. Methods: One hundred thirty‐nine patients treated with definitive IMRT (+/‐ concurrent chemotherapy) for head and neck mucosal cancers were included in this study. Patients were recommended a prophylactic feeding tube and followed up by a dietician for at least 8 weeks postradiotherapy (post‐RT). Potential prognostic factors were analyzed for risk and duration of feeding tube use for at least 25% of dietary requirements. Results: Many variables had significant effects on risk and/or duration of feeding tube use in univariate analyses. Subsequent multivariable analysis showed that T classification ≥3 and level 2 lymphadenopathy were the best independent significant predictors of higher risk and duration of feeding tube use, respectively, in oral cavity, pharyngeal, and supraglottic primaries. Conclusion: In patients treated with definitive IMRT, T classification ≥3 and level 2 lymphadenopathy can potentially stratify patients into 4 risk groups for developing severe dysphagia requiring feeding tube use.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherWiley Online
dc.publisher.placeUnited States
dc.relation.ispartofpagefrom2181
dc.relation.ispartofpageto2192
dc.relation.ispartofissue10
dc.relation.ispartofjournalHead and Neck
dc.relation.ispartofvolume40
dc.subject.fieldofresearchClinical sciences
dc.subject.fieldofresearchClinical sciences not elsewhere classified
dc.subject.fieldofresearchDentistry
dc.subject.fieldofresearchcode3202
dc.subject.fieldofresearchcode320299
dc.subject.fieldofresearchcode3203
dc.titlePretreatment risk stratification of feeding tube use in patients treated with intensity-modulated radiotherapy for head and neck cancer
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
gro.hasfulltextNo Full Text
gro.griffith.authorJackson, Jim E.


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