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  • Factors that modulate olfactory dysfunction

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    Beecher157903.pdf (879.2Kb)
    Author(s)
    Beecher, Kate
    St John, James A
    Chehrehasa, Fatemeh
    Griffith University Author(s)
    St John, James A.
    Chehrehasa, Fatemeh
    Beecher, Kate
    Year published
    2018
    Metadata
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    Abstract
    The olfactory system is one of a few areas in the nervous system which is capable of regeneration throughout the life. Olfactory sensory neurons reside in the nasal cavity are continuously replenished with new neurons arising from stem cells. Some factors such as aging, neurodegenerative diseases, head trauma, brain tumor extraction and infection cause olfactory dysfunction which significantly influences physical wellbeing, quality of life, mental health, nutritional status, memory processes, identifying danger and is associated with increased mortality. Therefore, finding a treatment to improve olfactory dysfunction is ...
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    The olfactory system is one of a few areas in the nervous system which is capable of regeneration throughout the life. Olfactory sensory neurons reside in the nasal cavity are continuously replenished with new neurons arising from stem cells. Some factors such as aging, neurodegenerative diseases, head trauma, brain tumor extraction and infection cause olfactory dysfunction which significantly influences physical wellbeing, quality of life, mental health, nutritional status, memory processes, identifying danger and is associated with increased mortality. Therefore, finding a treatment to improve olfactory dysfunction is needed. Recent research efforts in the field have shown some very promising new approaches to treat olfactory dysfunction. This review explores the current studies that have addressed therapeutic approaches to improve olfactory neuron regeneration based on cell transplantation therapy, modulation of physiological olfactory dysfunction and drug treatments.
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    Journal Title
    Neural Regeneration Research
    Volume
    13
    Issue
    7
    DOI
    https://doi.org/10.4103/1673-5374.235018
    Copyright Statement
    © The Author(s) 2018. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-Non-Commercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
    Subject
    Neurosciences not elsewhere classified
    Neurosciences
    Publication URI
    http://hdl.handle.net/10072/382877
    Collection
    • Journal articles

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