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dc.contributor.authorEl-Demerdash, Amr
dc.contributor.authorAtanasov, Atanas G
dc.contributor.authorBishayee, Anupam
dc.contributor.authorAbdel-Mogib, Mamdouh
dc.contributor.authorHooper, John NA
dc.contributor.authorAl-Mourabit, Ali
dc.date.accessioned2019-06-09T01:33:33Z
dc.date.available2019-06-09T01:33:33Z
dc.date.issued2018
dc.identifier.issn2072-6643
dc.identifier.doi10.3390/nu10010033
dc.identifier.urihttp://hdl.handle.net/10072/383482
dc.description.abstractPyrroloquinoline and guanidine-derived alkaloids present distinct groups of marine secondary metabolites with structural diversity that displayed potentialities in biological research. A considerable number of these molecular architectures had been recorded from marine sponges belonging to different marine genera, including Batzella, Crambe, Monanchora, Clathria, Ptilocaulis and New Caledonian starfishes Fromia monilis and Celerina heffernani. In this review, we aim to comprehensively cover the chemodiversity and the bioactivities landmarks centered around the chemical constituents exclusively isolated from these three marine genera including Batzella, Crambe and Monanchora over the period 1981–2017, paying a special attention to the polycyclic guanidinic compounds and their proposed biomimetic landmarks. It is concluded that these marine sponge genera represent a rich source of novel compounds with potential applications for cancer and other therapeutic areas.
dc.description.peerreviewedYes
dc.languageEnglish
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofissue1
dc.relation.ispartofjournalNUTRIENTS
dc.relation.ispartofvolume10
dc.subject.fieldofresearchNutrition and dietetics
dc.subject.fieldofresearchcode3210
dc.titleBatzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas
dc.typeJournal article
dc.type.descriptionC1 - Articles
dc.type.codeC - Journal Articles
dcterms.licensehttp://creativecommons.org/licenses/by/4.0/
dc.description.versionVersion of Record (VoR)
gro.rights.copyright© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
gro.hasfulltextFull Text
gro.griffith.authorHooper, John N.


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