dc.contributor.author | El-Demerdash, Amr | |
dc.contributor.author | Atanasov, Atanas G | |
dc.contributor.author | Bishayee, Anupam | |
dc.contributor.author | Abdel-Mogib, Mamdouh | |
dc.contributor.author | Hooper, John NA | |
dc.contributor.author | Al-Mourabit, Ali | |
dc.date.accessioned | 2019-06-09T01:33:33Z | |
dc.date.available | 2019-06-09T01:33:33Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 2072-6643 | |
dc.identifier.doi | 10.3390/nu10010033 | |
dc.identifier.uri | http://hdl.handle.net/10072/383482 | |
dc.description.abstract | Pyrroloquinoline and guanidine-derived alkaloids present distinct groups of marine secondary metabolites with structural diversity that displayed potentialities in biological research. A considerable number of these molecular architectures had been recorded from marine sponges belonging to different marine genera, including Batzella, Crambe, Monanchora, Clathria, Ptilocaulis and New Caledonian starfishes Fromia monilis and Celerina heffernani. In this review, we aim to comprehensively cover the chemodiversity and the bioactivities landmarks centered around the chemical constituents exclusively isolated from these three marine genera including Batzella, Crambe and Monanchora over the period 1981–2017, paying a special attention to the polycyclic guanidinic compounds and their proposed biomimetic landmarks. It is concluded that these marine sponge genera represent a rich source of novel compounds with potential applications for cancer and other therapeutic areas. | |
dc.description.peerreviewed | Yes | |
dc.language | English | |
dc.language.iso | eng | |
dc.publisher | MDPI | |
dc.relation.ispartofissue | 1 | |
dc.relation.ispartofjournal | NUTRIENTS | |
dc.relation.ispartofvolume | 10 | |
dc.subject.fieldofresearch | Nutrition and dietetics | |
dc.subject.fieldofresearchcode | 3210 | |
dc.title | Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas | |
dc.type | Journal article | |
dc.type.description | C1 - Articles | |
dc.type.code | C - Journal Articles | |
dcterms.license | http://creativecommons.org/licenses/by/4.0/ | |
dc.description.version | Version of Record (VoR) | |
gro.rights.copyright | © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | |
gro.hasfulltext | Full Text | |
gro.griffith.author | Hooper, John N. | |